Page 189 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPTEr 10 Chemokines and Chemokine Receptors 170.e1

MULTIPLE-CHOICE QUESTIONS

1. The major signal transduction pathway triggered by chemo- D. Chemokine-binding proteins that lack both chemokine
kines includes: and 7TM structure
A. Pertussis toxin sensitive heterotrimeric Gi proteins E. All of the above
B. Phospholipase C β 4. The chemokine system is involved in the pathogenesis of
C. Diacylglycerol which of the following diseases?
D. Phosphoinositide 3 kinase A. WHIM syndrome
E. All of the above
B. HIV/AIDS
2. Chemokine receptors are: C. Malaria
A. Rhodopsin-like G protein–coupled receptors D. All of the above
B. Localized in the nucleus
C. Encoded by certain bacterial species 5. The major homeostatic chemokine receptors include:
D. Used by intracellular bacteria for cell entry A. CCR7
B. CXCR3
3. The chemokine system includes: C. CCR6
A. Chemokines D. CCR1
B. Chemokine receptors
C. Seven-transmembrane (7TM) domain chemokine-binding
proteins