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CHaPter 46  Eosinophil-Associated Gastrointestinal Disorders            640.e1


              MUL ti PL e -CHO i C e  QU e S ti ONS

           1.  Eosinophilic esophagitis:                          3.  Eosinophilic gastroenteritis:
              A. Is the most  common  entity among  the eosinophil    A. Is a rare disease with unclear pathogenesis
               gastrointestinal disorders (EGIDs)                    B. Can be diagnosed only after exclusion of infections and
              B. During the natural course of the disease, often involves   intestinal allergies
               stomach and small bowel                               C. Can involve each segment of the gastrointestinal tract
              C. Is mainly triggered and driven by food-antigens     D. Swallowed topical steroids are currently considered as
              D. Immunoglobulin E (IgE)-based testing plays a crucial role   first-line drugs
               in the identification of causative foods
                                                                  4.  Hypereosinophilic syndromes:
           2.  Eosinophilic esophagitis:                             A. Have an unforeseeable and sometimes even fatal natural
              A. Must be treated only when a patient’s quality of life is   course
               markedly impaired                                     B. Involve mainly the gastrointestinal tract and seldom other
              B. Can be treated with drugs, diet, or dilatation        organ systems
              C. Dilatation is regarded as first-line treatment due to the    C. Encompass  a  group  of  entities  with  different  immune
               rapid symptom resolution                                pathogeneses
              D. Swallowed topical steroids and elimination diet have a    D. Require a comprehensive hematological and multisystem
               comparable efficiency                                   examination
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