Page 187 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 8 ■ Leukocytes: The Granulocytic and Monocytic Series 171

D mm m m ,

Nervous tissue m m m .

Functions of Macrophages

Lungs F , m m m
m k -

m m m .

M
Lymph nodes
m - k -

Bones mm (IFN-γ) - m
(G-CSF), m m z

Spleen m m m . T -

-m mm . I

Kidney
, m x x
m , m ( NF-α, ),
Connective tissue
or histiocytes m
.

Liver
FIGURE 8.13 M m. P

m . P m Life Span

m m Circulatory Phase

. M m m

m . N M
, x mm - m

. (A m C BJ, W DL. Memmler’s the Human m . M

Body in Health and Disease, , P , PA: L m - . O
W m & W k , , m .) m , m

m . T
m : . .

H m m M m -

k , x x m . . T m

CD ( , LPS), CD (F RIII) . M . × /L

m m , CCR ( m - . H , mm

m [MCP- ]). m m .

T m

: Tissue Phase

. C m CD CD CCR + Macrophages k , m ,
−
+
. I m m CD CD CCR + m m
+
+
. N m CD + ( ) CD CCR − m . W
+
m mm ,
T . T m .

:
A m

■ C m m m
m . - m .

m mm k A m m m

m - m m m

m .

m . T m m m -

■ I m m - . C k ,
, m m k , m , mm m -

, - - m -

mm m ( NF-α, IL- ). . T

■ N m - mm .
mm m M x “ x ” “ ” .

- . T S z m m -

m m “ ”

mm .