Page 261 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 13 ■ Bone Marrow Failure Syndromes 245

Infections

BOX 13.1 I q -

m . V , B, -

Etiologic Classi cation of Aplastic Anemia a C, m , E -B , m ,
m . B m (HPV)

DIRECT TOXICITY ,

Iatrogenic causes m m mm m -

Radiation m . T m m

Chemotherapy m q
Benzene x m ,

I m m m mm m m , m

IMMUNE-MEDIATED CAUSES m , - mm m .

Iatrogenic causes I , m
Transfusion-associated graft versus host disease m .

Eosinophilic fasciitis H - m -

Hepatitis-associated disease m m k

P . S

I m m m mm m . T

I m m m

a B - m m .
m . I m , -A,

-B, -C, -G. T -

m
m , z q k . S

m . m m mm

H , x K m m .

G W m m A m q ,

. k m -

B z m , m .

z . B z m z E m m

- , m m .

q , m m - A m m mm F E

m m . I , ( % % F E m % %

m z m m W ),

m q , , m ,

m . T ( ) x A.

m , H - m

x z . . I m k (HLA)-m

m -
Drugs
, mm m .
D m . U k

z , , f , Pathophysiology

m ,

q . T m - T pathophysiology mm m m ,

x m . T m

m . D x mm

m , m m m m ; x m-

. B , - m m

- . C mm

m m m - m -

( ). P , , . P

m m m .

m m %. H m m -

O m , m . T m f -

m , - m ( - m ,

, , z , m , m [CFU-S]) mm m ( - m

m . , mm [CFU-C]). T m m m