Page 316 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

300 PART 4 ■ Erythrocyte Disorders

D

PK z m . T

z m :

PKEnzyme
+
+
+
PEP ADP Mg 2+ → Pyruvate ATP

+
+
+
+
Pyruvate NADH H LDH Enzyme Lactate NNAD +
→
( UV Fluorescence ) ( No Fluorescence )

T NADH

m - (UV) ,

NAD .
FIGURE 16.6 G - - . (R m

A SC. Anderson’s Atlas o Hematology, P , PA:
W K H /L W m & W k , C Methem oglobin Reductase De ciency

, m .) H m x z m

m m . A x m %

m m m -
, W - m . H z m NADH-

( F . . ). m m

m m . A z m ,
Pyruvate Kinase NADH , m -

Pyruvate kinase PK def ciency % m j m M -

. T m mm , x x

z m z m G PD . T m m methemo-

PK. globin reductase de ciency m m -

PK m . T P x ( C

Am q PK , x ).

. T z q

% . % N Am , E , Acquired Hemolytic Anemia

A . A A Am -

q z . m m m- Etiology

m A W . Acquired hemolytic anemia

T m PK-LR PK. PK - m .

Em -M . S x m

M k m x q m m B x . .

A P. A A m j x m

PK q A P , m m

k , m m , m m mm

, m m . T .

q m -

m m . Chem icals and Venom s

PK- I m m x -

m , A P , m m . F ,

. L A P -

, - (DPG), x . T m m ,

, , . m m- . L m , ,

m . A P

I G PD x . m .

I , , - V m m m k m

, z m

PK . m (DIC).

P m PK

m m , m Physical Agents

m ( - H m .

). P , -DPG B m x ,

m z m k. m m m . T