Page 372 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

356 PART 5 ■ Nonmalignant Leukocyte Disorders

TABLE 19.2 Causes of Lymphocytosis

Lymphocytosis Associated w ith Atypical Lymphocytes

% of White Cells That Are Atypical Lymphocytes

Lymphocytosis Associated w ith
>20% <20% Small Mature Lymphocytes

Infectious mononucleosis Mumps,* varicella,* rubeola, rubella, atypical Reactive lymphocytosis

Infectious hepatitis pneumonia, herpes simplex, herpes zoster, Pertussis

Posttransfusion syndrome roseola infantum, in uenza,* other viral ill-

CMV infection nesses, tuberculosis,* rickettsialpox, brucel-

pn-Aminosalicylic acid (PAS) losis,* toxoplasmosis,* radiation

Phenytoin (Dilantin) and mephenytoin

(Mesantoin) hypersensitivity

Agranulocytosis

Lead intoxication

Stress

Leukemias and lymphomas*

*Higher counts of atypical lymphocytes are occasionally found.

M m Epidem iology

. L m k m ( m ) A EBV m m

. T k m m m ,

. W m’ m m m

. C . U , -
m EBV x -

k .

T q seronegativity %
DISORDERS ASSOCIA ED WI H , m

LYMPHOCY OSIS m , %

Infectious Mononucleosis . A m x , -
mm

I m , , . I W , m x

- m lymphoproliferative Epstein- EBV . A x m -

Barr virus (EBV). EBV B k ’ m m , x ;

m m m m (

A ; m ; - ). A x m % m -

m m , , x. .

I k k
Etiology . EBV m m mm m-

EBV , m m j m

m . EBV m . I m mm m m . I mm -

% ’ x , , EBV m

m k m q k . % %. B m mm

EBV m DNA . I m - mm m m -

, B m , k m

m m . I m -

m x m - m – k -

. O m m CMV

m B m EBV.

m m A x m m-

x (F . . ). . R