Page 374 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )
P. 374

358            PART 5  ■  Nonmalignant Leukocyte Disorders





                       800



                                                                                        Henke et al.
                       700                                                              Health et al.

                                                                                        Davidson
                     n
                     o  600
                     i
                     t
                     a
                     l
                     u
                     p
                     o  500
                     p

                     0
                     0
                     0
                     ,
                     0  400
                     0
                     1

                     r
                     e
                     p  300

                     s
                     e
                     s
                     Ca  200                                                                                                          Large "atypical"                                        Normal
                                                                                                                                         lymphocyte                                       lymphocyte


                                                                                                                           FIGURE 19.3  T                                 m                   . T            “       -
                       100
                                                                                                                                 ”    m                                     . (R                  m M  C             H. Te
                                                                                                                           Nature o  Disease Pathology  or the Health Pro essions, P                  , PA:

                                                                                                                           L               W      m  & W  k    ,         ,             m        .)
                                        5        10        15        20         25        30        35        40

                                                               Age (years )

               FIGURE  19.2  I                                                m

                                           .                                                                                                                        m               m mm                   .
                                                                                                                           H                                m                               m

                                                                                                                                                             (       ),                       :
                    m                               . A  m                                                                                                                                                           -

                                       m                        m                            m        .                            m                    . R

               B                     m                             m                           EBV-                                                                                                   . T

                                             m                                 CMV-

               m                    , EBV m                                                                                           .

                                              . A                     m                                                         W                                        ,     %         %

                               m                                m                                                                                             m

                  m     m .                                                                                                                                              . T



               Laboratory Data


               L                                                                                m                                                        Descriptive Features of the

                                                   m                   .  H  m                                                                           Classic Dow ney Classi  cation of

                                            k                                         m                                         TABLE        19.3        Lymphocytes Seen in Infectious

                  ×    /L              x m                                        ;                                                                      Mononucleosis

                 %                                                      m              leu-

               kopenia. A                        k                    m                      -                                 Type I

                                           ,                  m                                                                Nucleus                   May be irregularly shaped

                       m                                                  .

                  m                                       m     %         %,          %                                        Cytoplasm                 Usually many cytoplasmic vacuoles

                  %                  m              .                             m                                                                      Dark blue (basophilic)

               (F   .      .  )    x                      m                                                                    Type II

                                       m                m                                                                      Nucleus                   Chromatin is coarse and clumped

                          m                        .  I                 ,

               D           C                   (              .  )                                                             Cytoplasm                 Increased amount

                            m             . E         -B                          m      -                                                               Dark blue (basophilic) around the periphery

                                                             CD    .                                                                                     or in a radial pattern

                    I                                     m     m                      m          -                                                      A few cytoplasmic vacuoles

                                         ,                                       m                                             Type III*

                  m         f            m  k  . T                   m                                                         Nucleus                   Nucleoli usually visible

                                            . T

                               m                                                   EBV             -                                                     Enlarged in size

                   .  H                                      m                                            -                    Cytoplasm                 Dark blue (basophilic)

                   . T                                                             m                                           *This cell resembles an immature lymphocyte.
   369   370   371   372   373   374   375   376   377   378   379