Page 405 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 21 ■ Acute Leukemias 389

m mm k m

m , m -

m . T m : m

FAB M : . T m m .

m .

Clinical Signs and Sym ptom s

FAB M z

m m . T m

, , , .

P x m m ,

m; m m m-

; ; . A

m m , m , m -
FIGURE 21.3 A m k m M . (R m ; , x m % x

M C KD. Clinical Laboratory Medicine, , P , m m .

PA: L W m & W k , , m .)
C m AML

m ALL. O z m m
m m k M m m

. M m k k - AML. I m ,

m . M q z m MPO

k m ( . ).
. T m chlo-

roma. I m , m
FAB M0
AML.

FAB M m WHO AML

z (NOS) (F . . ). T Laboratory Data

m ( x m % A m m x m

AML) % AML . L k m

. P , k

m m k m × /L.

m . AML, m m - T m x m

, m . T m mm , m mm

m mm m k- m k m . I

/ . Imm m m mm m -

. E m z , k m k m (FAB M ).

m , , m . T m T m

k m . (F . . ) m m %

Am m m k m , m m % m . T -

m mm . W m m , - Auer

, , AML -

, FAB M x m % .

M M m j .

T mm FAB M FAB M .

Acute Myeloid Leukemia (FAB M1)

T WHO m m -

k m m . T m k m

Examples of Monoclonal Antibody
TABLE 21.8
Classi cation of Acute Leukemias

Myeloid lineage CD13, CD3, CD15, MPO, CD117

T-cell lineage CD2, CD3, CD5, CD7

B-cell lineage CD19, CD20, CD22, CD79a FIGURE 21.4 A m k m M . (R m
M C KD. Clinical Laboratory Medicine, , P ,
Megakaryoblastic CD41, CD61
PA: L W m & W k , , m .)