Page 488 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

472 PART 6 ■ Neoplastic Disorders

REVIEW QUESTIONS (continued)

5. Which o the ollowing is pre o in nt e ture o 11. he tot l leukocyte count in CML usu lly is

essenti l thro bocythe i co p re with other types × 10 /L.
9
o MPNs? A. nor l

A. V ri ble nu ber o pl telets B. <25

B. Mo er tely incre se nu ber o pl telets C. <50

C. Extre ely incre se nu ber o pl telets D. >50

D. Incre se rrow f brosis

12. Te Phil elphi chro oso e is typic lly ssoci te

6. In MPN, the test results o isor ers o he ost sis n with

co gul tion th t re ost likely to be bnor l re A. cute yelogenous leuke i

A. ecre se pl telet count, incre se AP , n B. leuke oi re ctions

incre se ctor V level C. cute ly phobl stic leuke i

B. incre se AP , ecre se ctor V level, n D. CML

incre se concentr tion o ntithro bin III in

ny 13. P tients with PRV su er ro

C. ecre se AP , ecre se ctor V level, n A. leuke ic inf ltr tion

incre se concentr tion o d- i ers B. bone rrow f brosis

D. ecre se concentr tion o d- i ers, ecre se C. hypervole i

concentr tion o ntithro bin III, n incre se D. ne i

concentr tion o pl s in- lph 2-pl s in inhibitor

co plex 14. In PRV, cytogenetic results o not pre ict/provi e

A. ur tion o the ise se

7. Inter eron lph h s been shown to B. consequences o yelosuppressive ther py

A. sti ul te triline ge cell proli er tion C. clues to he tologic l phenotype

B. suppress proli er tion o he topoietic progenitor D. evolution o the ise se

cells

C. sub ue erythropoiesis only 15. Hyperviscosity c n pro uce

D. suppress eg k ryocytopoiesis only A. ne i

B. izziness

8. A leuke i o long ur tion th t ects the neutrophilic C. he orrh ges

gr nulocytes is re erre to s D. psychotic epression

A. cute ly phobl stic leuke i

B. cute yelogenous leuke i 16. T e jor criteri or i gnosis o PRV inclu e ll o the

C. cute onocytic leuke i ollowing except

D. CML A. incre se re bloo cell ss

B. presence o JAK2V617F

9. Te lk line phosph t se cytoche ic l st ining re c- C. hypercellul r bone rrow

tion is use to i erenti te between D. spleno eg ly

A. chronic ly phobl stic leuke i n cute yelog-

enous leuke i 17. Incre se bloo viscosity in p tients with PRV c n c use

B. cute ly phobl stic leuke i n cute yelog- ngerous con ition o

enous leuke i A. hot ushes

C. CML n severe b cteri l in ections B. shortness o bre th

D. leuke oi re ctions n severe b cteri l in ections C. high RDW

D. v scul r occlusion

10. P tients with the initi l ph se o CML re prone to

A. weight g in, e e , n tigue 18. Te level o erythropoietin in the urine is in

B. e e , ne i , n splenic in rction p tients with PRV co p re with other kin s o

C. low-gr e evers, night swe ts, n splenic in rction polycythe i .

D. pro inent ly ph enop thy n night swe ts A. incre se

B. the s e

C. v ri ble

D. ecre se