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474            PART 6  ■  Neoplastic Disorders




                                                                                                                           Kr  lovics R, et   l. A g  in-o - unction   ut  tion o  JAK2 in   yeloproli -
                  COMPANION RES OURCES
                                                                                                                                 er  tive   isor  ers, N Engl J Med, 352(17):1779–1790, 2005.

                                                                                                                           Klippel S, et   l. Bioche  ic  l ch  r  cteriz  tion o  PV-1,    novel he    to-
                  http://thepoint.lww.co  /  urgeon6e
                                                                                                                                 poietic cell sur   ce receptor, which is overexpresse   in polycythe-

                  E  ch stu  ent is encour  ge   to   ccess   n   use the Web-                                                    i   rubr   ver  , Blood, 100(7):2441–2448, 2002.

                  b  se   co  p  nion resources   evelope    or this ch  pter.                                             L  rson RA. Is there    best   KI  or chronic ph  se CML? Hematology Am

                  Here, you will f n         ition  l le  rning tools to incre  se                                               Soc Hematol Educ Program, 2015:250–256.

                  your un  erst  n  ing o  the concepts   n   clinic  l   pplic  -                                         Lee SJ, et   l. I  p  ct o  prior i    tinib   esyl  te on the outco  e o  he    -

                  tions o  the ch  pter.                                                                                         topoietic cell tr  nspl  nt  tion  or chronic   yeloi   leuke  i  , Blood,
                                                                                                                                 112(8):3500–3507, 2008.

                                                                                                                           Levine  RL,  Gillil  n    G.  Myeloproli er  tive    isor  ers,  Blood,
                                                                                                                                 112(6):2190–2198, 2008.

               BIBLIOGRAPHY                                                                                                M  rtinelli G, et   l. New tyrosine kin  se inhibitors in chronic   yeloi

                                                                                                                                 leuke  i  , Haematologica, 90(4):534–541, 2005.

               Bowers GR (e  .). Polycythe  i   rubr   ver  , CDH Oncol, 7(7):1–6, 2003.                                   M  sc  renh  s J. Looking  orw  r  : novel ther  peutic   ppro  ches in
               C    pbell PJ, Green AR. T e   yeloproli er  tive   isor  ers, N Engl J Med,                                      chronic   n       v  nce   ph  ses o    yelof brosis, Hematology Am Soc

                     355(23):2452–2466, 2006.                                                                                    Hematol Educ Program, 2015:329–336.

               Cl  rk M. Chronic   yelo  onocytic leuke  i   tr  ns or  ing into   cute                                    Mu  precht S, et   l. I    tinib   esyl  te selectively i  p  irs exp  nsion o
                       yelogenous leuke  i  , Lab Med, 40(1):19–21, 2009.                                                          e  ory cytotoxic    cells without     ecting the control o  pri    ry

               Conley CL. Polycythe  i   ver  , JAMA, 263(18):2481–2483, 1990.                                                   vir  l in ections, Blood, 108(10):3406–3413, 2006.

               Cris  n D, C  rr ER. BCR/  bl gene re  rr  nge  ent in chronic   yeloge-                                    O’Brien SG, et   l. I    tinib co  p  re   with inter eron   n   low-  ose

                     nous leuke  i     n     cute leuke  i  s, Lab Med, 23(11):730–735, 1992.                                    cyt  r  bine  or newly   i  gnose   chronic-ph  se chronic   yeloi

               D  o K  ,   yner JW. Wh  t’s   i  erent   bout   typic  l CML   n   chronic                                       leuke  i  , N Engl J Med, 348(11):994–1004, 2003.
                     neutrophilic leuke  i  ? Hematology Am Soc Hematol Educ Program,                                      P  l  n  ri F, et   l. Chronic   yeloi   leuke  i   in bl  st crisis tre  te   with

                     2015:264–270.                                                                                               i    tinib 600   g: outco  e o  the p  tients   live     er    6-ye  r  ollow-

               Deininger MW. Molecul  r   onitoring in CML   n   the prospects  or                                               up, Haematologica, 93(12):1792, 2008.
                     tre  t  ent- ree  re  issions,  Hematology  Am  Soc  Hematol  Educ                                    Peggs  K,  M  ckinnon  S.  I    tinib    esyl  te—the  new  gol    st  n-

                     Program, 2015:257–262.                                                                                         r    or tre  t  ent o  chronic   yeloi   leuke  i  , N Engl J Med,

               Drucker BJ.   r  nsl  tion o  the Phil    elphi   chro  oso  e into ther  py                                      348(11):1048–1050, 2003.

                      or CML, Blood, 112(13):4808–4817, 2008.                                                              Quintás-C  r         A, Cortes J. Molecul  r biology o  bcr-  bl1-positive

               Eg  n JM.     rgeting ste  -cells in chronic   yeloi   leuke  i   with                                            chronic   yeloi   leuke  i  , Blood, 113(80):1619–1630, 2009.
                     PPAR-  lph     gonist, N Engl J Med, 373(20):1973–1975, 2015.                                         R    i   D, Geyer HL. M  n  ge  ent o  sy  pto  s in polycythe  i   ver

               F  b  rius A, et   l. Dyn    ics o  cytogenetic   berr  tions in Phil    elphi                                     n   essenti  l thro  bocythe  i   p  tients,  Hematology  Am  Soc

                     chro  oso  e positive   n   neg  tive he    topoiesis   uring     s  tinib                                  Hematol Educ Program, 2015:340–348.
                     ther  py o  chronic   yeloi   leuke  i   p  tients     er i    tinib    ilure,                        R  n  olph   . JAK2: the next BCR/ABL     ong the   yeloproli er  tive

                     Haematologica, 92(6):834–837, 2007.                                                                          isor ers (MPN)? ACLS   oday, 22(5):5–11, 2008.

               F    erl S, et   l. T e biology o  chronic   yeloi   leuke  i  , N Engl J Med,                              Rowe JM. Closing the g  p in CML, Blood, 109(6):2271, 2007.

                     341(3):164–172, 1999.                                                                                 S  glio G. Me  suring   olecul  r response in CML: proble  s   n   signif -

               Fouc  r K. CSP 2015 Short Course, Leukemia Classif cation 2016: What,                                             c  nce. In: Imatinib—Impact on CML Management and Beyond, 8th
                     When, “Who,” S  cr    ento, CA: C  li orni   Society o  P  thologists,                                      EHA Congress, Lyon, Fr  nce, 2003.

                     2015.                                                                                                 Sch  ich M, et   l. Prognosis o    cute   yeloi   leuke  i   p  tients up to

               Hehl    nn R, S  ussele S.   re  t  ent o  chronic   yeloi   leuke  i   in                                        60 ye  rs o    ge exhibiting triso  y 8 within    non-co  plex k  ryo-
                     bl  st crisis, Haematologica, 93(12):1765–1768, 2008.                                                       type: in  ivi  u  l p  tient     t  -b  se     et  -  n  lysis o  the Ger    n

               Hochh  us A. Molecul  r response   n   resist  nce to I    tinib (Glivec®.                                         cute    yeloi    leuke  i   intergroup,  Haematologica,  92(6):
                                                                                                                  )
                     In:  Education  Book  o   the  8th  EHA  Congress,  Lyon,  Fr  nce,                                         763–770, 2007.

                     2003:15–20.                                                                                           Schi  er CA. BCR-ABL tyrosine kin  se inhibitors  or chronic   yelog-

               Hochh  us  A.  Perspectives  on      n  ging  resist  nce  in  CML.  In:                                          enous leuke  i  , N Engl J Med, 357(3):258–265, 2007.
                     Imatinib—Impact on  CML Management and Beyond,  8th  EHA                                              Schw  rtz R. A   olecul  r st  r in the w  rs   g  inst c  ncer, N Engl J Med,

                     Congress, Lyon, Fr  nce, 2003.                                                                              347(7):462–463, 2002.

               K  nt  rji  n HM, et   l. Long-ter   surviv  l benef t   n   i  prove   co  -                               Scott LM, et   l. JAK2 exon 12   ut  tions in polycythe  i   ver     n   i  io-
                     plete  cytogenetic    n      olecul  r  response  r  tes  with  i    tinib                                  p  thic erythrocytosis, N Engl J Med, 356(5):459–468, 2007.

                      esyl  te  in  Phil    elphi    chro  oso e-positive  chronic-ph  se                                  S  yth MJ. I    tinib   esyl  te—uncovering       st tr  ck to       ptive

                     chronic    yeloi    leuke  i        er     ilure  o   inter eron-α,  Blood,                                 i    unity, N Engl J Med, 354(21):2282–2284, 2006.

                     104(7):1979–1988, 2006.                                                                               Stu  rt  BJ,  Vier    AJ.  Polycythe  i    ver  ,  Am  Fam  Physician,  69:

               K  nt  rji  n H, et   l. Nilotinib in i    tinib-resist  nt CML   n   Phil    elphi                               2139–2144, 2146, 2004.
                     chro  oso  e-positive  ALL,  N  Engl  J  Med,  354(24):2542–2551,                                         lp  z M. D  s  tinib in i    tinib-resist  nt Phil    elphi   chro  oso  e-

                     2006.                                                                                                       positive leuke  i  s, N Engl J Med, 354(24):2531–2540, 2006.
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