Page 563 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 27 ■ Principles of Hemostasis and Thrombosis: Blood Coagulation Factors and Natural Coagulant Systems 547

REVIEW QUESTIONS (continued)

19. Te na co on athway o the intrinsic-extrinsic 26. Neither the AP nor the P etects a e ciency o

athway is A. ate et actor 3

A. actor X activation B. actor VII

B. actor II activation C. actor VIII

C. actor I activation. D. actor IX

D. actor XIII activation.

27. Te unction o thro bo astin in the rothro bin

20. Prothro bin to thro bin conversion is acce erate by test is to rovi e to the assay.

A. a co ex o activate actors IX an VII A. kao in

B. actor V an ionize ca ciu B. brinogen

C. a co ex o hos ho i i s an actor VII C. hos ho i o rotein

D. a co ex o activate actors X an V D. thro bin

21. Fibrinogen is converte to brin ono ers by 28. An abnor a y ro onge AP ay in icate

A. rothro bin A. a severe e etion o brinogen

B. thro bin B. the resence o a circu ating anticoagu ant

C. ca ciu ions C. actor VIII e ciency

D. actor XIIIa D. a o the above

22. Te inactive as inogen is activate to by ro- 29. I a chi ingeste rat oison, which o the o owing

teo ytic enzy es. tests shou be er or e to test the e ect o the oi-

A. rothro bin son on the chi ’s coagu ation echanis ?

B. as in A. AP

C. as a ka ikrein B. P

D. as a thro bo astin antece ent C. Fibrinogen assay

D. Tro bin ti e

*23. Which o the o owing state ents are true o the bri-

no ytic syste ? *30. Which o the o owing con itions can cause an

A. P as in igests brin an brinogen increase thro bin ti e?

B. T e active enzy e o the syste is as in A. Fibrin s it ro ucts

C. Inactive as inogen circu ates in the as a unti B. High concentrations o i unog obu ins

an injury occurs C. He arin thera y

D. A o the above D. A o the above

24. I a e iatric reo erative atient has a a i y history 31. He arin inhibits the c otting o b oo by neutra izing

o b ee ing but has never ha a b ee ing e iso e her- the e ect o

se , what test shou be inc u e in a coagu ation ro- A. thro bin

e in a ition to the P , AP , an ate et count? B. ca ciu ions

A. Lee-White c otting ti e C. ate ets

B. C ot retraction D. actor VIII

C. B ee ing ti e

D. Fibrin s it ro ucts *32. A atient has a ro onge AP an a nor a P .

T e AP is not correcte by actor VIII– e cient

*25. A atient with a severe ecrease in actor X activity as a but is correcte by actor IX– e cient as a.

wou e onstrate nor a In which actor oes the atient a ear to be e cient?

A. AP A. Factor II

B. P B. Factor V

C. thro bin ti e C. Factor VIII

D. b ee ing ti e D. Factor IX

(continued)