Page 564 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

548 PART 7 ■ Principles and Disorders of Hemostasis and Thrombosis

REVIEW QUESTIONS (continued)

33. T e nor a rotective echanis s against thro bosis 36. Which o the o owing characteristics is (are) true o

inc u e rotein S?

A. the f ow o b oo A. It is a co actor o rotein C.

B. the action o antithro bin. B. It increases the rate o inactivation o actor Va.

C. rotein C an rotein S C. It enhances the bin ing o activate rotein C to

D. a o the above hos ho i i s.

D. A o the above.

34. I he arin thera y is initiate in a atient, a ecrease

anticoagu ant res onse can be cause by ecrease ev- 37. Antithro bin is the rinci a hysio ogica inhibitor o

e s o A. thro bin

A. ate et actor 3 B. actor Xa

B. ate et actor 4 C. actor XIa

C. antithro bin D. both A an B

D. actor XIII

38. Which o the o owing is not correct regar ing ce u ar

35. Which o the o owing is (are) characteristic o rotein roteases?

C? A. T ey b ock the activation or action o as in.

A. It is not vita in K e en ent. B. T ey inc u e a ha-2 inhibitor.

B. It is or e in res onse to thro bin generation. C. T ey ra i y neutra ize the brino ytic ro erties o

C. It inactivates actors Va an VIIIa. as in.

D. Both B an C. D. T ey artici ate in c ot or ation.

D’Ange o A, et a . Co arison o ean nor a rothro bin ti e
COMPANION RES OURCES with P o resh nor a oo e as a or o a yo hi ize contro

as a (R82A) as eno inator to ex ress P resu ts: Co aborative
htt ://the oint. ww.co / urgeon6e
Stu y o the Internationa Fe eration o C inica Che istry, Clin

Each stu ent is encourage to access an use the web- Chem, 43(11):2169–2174, 1997.

base co anion resources eve o e or this cha ter. e Fouw NJ, et a . T e co actor ro e o rotein S in the acce eration

Here, you wi n a itiona earning too s to increase o who e b oo c ot ysis by activate rotein C in vitro, Blood,

your un erstan ing o the conce ts an c inica a ica- 67(4):1189–1192, 1986.

tions o the cha ter. Devreese KMJ. Inter retation o nor a as a ixing stu ies in
the aboratory iagnosis o u us anticoagu ants. Trom Res,

2007;119(3):369–376.

Fair DS, et a . Hu an en othe ia ce s synthesize rotein S, Blood,
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