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CHAPTER 30  ■  Instrumentation in Hematology                             643







                                 CASE STUDIES






                        Case Study 30.1




                     ■    Laboratory Data
                     A 28-year-old white woman had the  ollowing erythrocyte

                     results:



                     RBC count 3.2 × 10 /L
                                                      12
                     Hemoglobin 8.7 g/dL


                     Hematocrit 26%
                     MCV 81  L


                     MCH 19 pg
                     MCHC 27.2 g/dL                                                                                             ■    Critical Thinking Group Discussion Questions


                     RCMI 13.2                                                                                                  1.  Do the histogram or other erythrocyte results demon-
                                                                                                                                      strate any abnormalities?

                     Her RBC histogram appears below. All other parameters

                     were within normal ranges.                                                                                 2.  What type o  disorder, i  any, is suggested by the RBC
                                                                                                                                      results and histogram?



                                                                                                                                3.  What  urther laboratory testing should be considered?




                                                                                                                                    Case Study 30.3



                                                                                                                                ■    Laboratory Data
                                                                                                                                A 57-year-old white man with a total leukocyte count o  15 ×

                                                                                                                                10 /L had a three-part leukocyte di  erential:
                                                                                                                                    9


                                                                                                                                Lymphocytes 68%

                                                                                                                                Mononuclear cells 4%

                     ■    Critical Thinking Group Discussion Questions                                                          Granulocytes 28%
                     1.  Do the histogram or other erythrocyte results demon-                                                   Absolute lymphocyte value 10.2 × 10 /L
                                                                                                                                                                                              9
                           strate any abnormalities?                                                                            Absolute granulocyte value 4.2 × 10 /L
                                                                                                                                                                                            9


                                                                                                                                T e WBC histogram appears below. All other parameters
                     2.  What type o  disorder, i  any, is suggested by the RBC

                           results and histogram?                                                                               were within normal ranges.




                     3.  What  urther laboratory testing should be considered?





                        Case Study 30.2




                     ■    Laboratory Data                                                                                       ■    Critical Thinking Group Discussion Questions

                     A 48-year-old black woman had the  ollowing RBC results:                                                   1.  Do the histogram or other leukocyte results demonstrate


                     RBC 2.36 × 10 /L                                                                                                 any abnormalities?
                                              12
                     Hemoglobin 8.6 g/dL

                     Hematocrit 27%                                                                                             2.  What type o  disorder, i  any, is suggested by the WBC

                     MCV 114  L                                                                                                       results and histogram?

                     MCH 36.4 pg                                                                                                3.  What  urther laboratory testing should be considered?

                     MCHC 32 g/dL

                     RDW 28%                                                                                                        Case Study 30.4



                     Her RBC histogram appears below. All additional param-

                     eters were within normal ranges.                                                                                ■ Laboratory Data
                                                                                                                                A 14-year-old white girl with a total leukocyte count o

                                                                                                                                29 × 10 /L had the  ollowing histogram results:
                                                                                                                                             9


                                                                                                                                Lymphocytes 15%

                                                                                                                                Mononuclear cells 48%

                                                                                                                                Granulocytes 37%



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