Page 321 - Review of Medical Microbiology and Immunology ( PDFDrive )
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                 310
                       PART IV  Clinical Virology
                 2.  Regarding human papillomavirus (HPV), which one of the fol-
                                                                       (C)  Penile intraepithelial neoplasia associated with HPV-6
                   lowing statements is most accurate?
                                                                       (D)  Penile intraepithelial neoplasia associated with HPV-16
                   (A)  There is no vaccine available against HPV.
                   (B)  Acyclovir is effective in preventing lesions caused by HPV but
                      does not cure the latent state.
                                                                     ANSWERS
                   (C)  Antigen–antibody complexes  play an important  role in  the
                      pathogenesis of warts caused by HPV.
                   (D)  The early proteins of HPV play a more important role in malig-
                      nant transformation than the late proteins.
                                                                     3.  (C)
                   (E)  The diagnosis of HPV infection is usually made by detecting   1.  (B)
                                                                     4.  (D)
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 mebooksfree.com  mebooksfree.com           mebooksfree.com          PRACTICE QUESTIONS: USMLE &  mebooksfree.com                          mebooksfree.com
                      cytoplasmic inclusions within giant cells in the lesions.
                 3.  Regarding parvovirus B19, which one of the following statements
                   is most accurate?
                   (A)  A  vaccine  is  available  that  contains  killed  virus  as  the
                                                                     SUMMARIES OF ORGANISMS
                      immunogen.
                   (B)  Patients infected by parvovirus B19 can be diagnosed in the
                                                                     Brief summaries of the organisms described in this chapter
                      laboratory using the cold agglutinin test.
                                                                     begin on page 670. Please consult these summaries for a rapid
                   (C)  Parvovirus B19 causes a severe anemia because it preferentially
                                                                     review of the essential material.
                      infects erythrocyte precursors such as erythroblasts.
                   (D)  It commonly infects neutrophils, resulting in an immunodefi-
                      ciency that predisposes to infections by pyogenic bacteria.
                   (E)  Parvoviruses have a double-stranded DNA genome but require
                      a DNA polymerase in the virion because they replicate in the
                      cytoplasm.                                     COURSE EXAMINATIONS
 mebooksfree.com  mebooksfree.com           mebooksfree.com          Board) Practice Questions starting on page 723. Also see Part         mebooksfree.com
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                 4.  A 24-year-old woman is seen by her gynecologist for a routine Pap
                                                                     Questions on the topics discussed in this chapter can be found
                   smear. The smear shows cervical intraepithelial neoplasia grade 3
                                                                     in the Clinical Virology section of Part XIII: USMLE (National
                   (CIN 3). You decide to examine her long-term male sexual part-
                   ner. Which one of the following is the most likely finding?
                                                                     XIV: USMLE (National Board) Practice Examination starting
                   (A)  Condylomata lata
                                                                     on page 751.
                   (B)  Condylomata acuminata



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