Page 440 - Review of Medical Microbiology and Immunology ( PDFDrive )

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CHAPTER 51 Intestinal & Urogenital—Protozoa
Giardiasis
(Giardia lamblia)
2
KEY
I
I
Infective stage
D
Diagnostic stage

mebooksfree.com mebooksfree.com Contamination of food passed in stool but mebooksfree.com mebooksfree.com mebooksfree.com
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or water with cysts.
Trophozoites are also

they do not survive in
the environment.

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mebooksfree.com mebooksfree.com mebooksfree.com D mebooksfree.com mebooksfree.com
1
I
Cyst
D

FIGURE 51–6
Giardia lamblia. Life cycle. Top blue arrow shows cysts being ingested. Within the intestine, the cyst produces trophozoites
that cause diarrhea. Bottom blue arrow shows cysts and trophozoites being passed in the stool and entering the environment. Red arrow indi-
cates survival of cysts in the environment. (Source: Dr. Alexander J. da Silva and Melanie Moser, Centers for Disease Control and Prevention.)

of string until it reaches the duodenum, may be useful. The
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trophozoites adhere to the string and can be visualized after
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withdrawal of the string.

The treatment of choice is either tinidazole (Tinidamax) or
metronidazole (Flagyl). Tinidazole is better tolerated.

Prevention
Prevention involves drinking boiled, filtered, or iodine-
treated water in endemic areas and while hiking. No pro-
phylactic drug or vaccine is available.

mebooksfree.com mebooksfree.com mebooksfree.com CRYPTOSPORIDIUM mebooksfree.com mebooksfree.com
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Disease
Cryptosporidium hominis causes cryptosporidiosis, the
FIGURE 51–7
Giardia lamblia—trophozoite. Arrow points to a
main symptom of which is diarrhea. The diarrhea is most
pear-shaped trophozoite of G. lamblia. (Source: Dr. M. Mosher, Centers for
severe in immunocompromised patients (e.g., those
Disease Control and Prevention.)

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