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Biology Term 1  STPM  Chapter 2 Structure of Cells and Organelles








                                                         Intermediate
                                                         filament
                                                                                                              2
                                                   Microfilament
                   Microtubule
                                                                                   Arrangement of tubulin
                                Cytoskeleton
                                     Figure 2.10  Cytoskeleton and arrangement of tubulin in microtubule

                         (vii) The functions of microtubules are as follows:
                             •  They form the cytoskeleton that determines the shape of
                               the cell.
                             •  They  can  divide  the  cytoplasm  of  the  cell  into
                               compartments  so that specialised enzymes can be
                               isolated from others to function better.
                             •  They  can  contract, causing movement in the cilia and
                               flagella.
                             •  They  can  pull  chromosomes  or  chromatids  during
                               mitosis or meiosis.
                             •  They  can  cause  the  movement of organelles, including
                               mitochondria, lysosomes and vesicles to move along like
                               railway tracks.
                     (b)  Microfilaments
                         (i)  The microfilaments are fine filaments made of protein with
                             a diameters of 7 nm and lengths of several µm.
                         (ii)  They are composed of one or two types of protein including
                             actin and myosin.
                         (iii)  They are  dynamic which means they can change their
                             length very quickly depending on their locations and
                             functions.
                         (iv)  Each type of protein forms  subunits  that are arranged
                             helically.
                         (v)  The subunits can  slide  over one another causing  the
                             microfilaments to contract.
                         (vi)  Microfilaments exist in  bundles  and they are normally
                             found in layers in the cytoplasm.






                                    Two strands of
                                    actin subunits
                              Microfilament composed of two                Intermediate filament with eight
                               strands of protein subunits                   strands of protein subunits
                                           Figure 2.11  Microfilament and intermediate filament


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