Page 18 - 02ed2018
P. 18
However, despite the fact that the overall risk of oral steroids being truly liver-toxic may be overstated, I
believe it’s good practice to err on the side of caution and mimic some of the more old-school practices:
limit oral use to brief periods (or stick to injectables), and definitely avoid stacking too many orals at the
same time.
References:
1. J Clin Gastroenterol. 2002 Oct;35(4):350-2. Androgenic/Anabolic steroid-induced toxic hepatitis.
Stimac D, Milić S, Dintinjana RD, Kovac D, Ristić S.
2. Clin Ther. 2001 Jun;23(6):789-801; discussion 771. Review of oxymetholone: a 17alpha-alkylated
anabolic-androgenic steroid.Pavlatos AM1, Fultz O, Monberg MJ, Vootkur A, Pharmd.
3. HIV Hotline. 1998 Dec;8(5-6):10-1. Does the choice of alpha-AAS really make a difference?
Mutzebaugh C.
4. Minerva Med. 1971 Jun 27;62(51):2605-11. [Hepatotoxicity of anabolic steroids]. Rozman C, Urbano A,
Galera H.
5. J Gastroenterol 2000;35(7):557-62, Multiple hepatic adenomas caused by long-term administration of
androgenic steroids for aplastic anemia in association with familial adenomatous polyposis. Nakao A,
Sakagami K, Nakata Y, Komazawa K, Amimoto T, Nakashima K, Isozaki H, Takakura N, Tanaka N.
6. Medical Hypotheses 93 (2016) 150–153. Anabolic androgenic steroid-induced hepatotoxicity. Peter
Bond, William Llewellyn, Peter Van Mol
7. Med Sci Sports Exerc. 1999 Feb;31(2):243-50, Rat liver lysosomal and mitochondrial activities are
modified by anabolic-androgenic steroids. Molano F, Saborido A, Delgado J, Moran M, Megias A.
8. Lancet 1979 Nov 24;2(8152):1120-3, Hepatic angiosarcoma associated with androgenic-anabolic
steroids. Falk H, Thomas LB, Popper H, Ishak KG.
9. J Pharmacol Toxicol Methods 1995 Aug;33(4):187-95, Toxic effects of anabolic-androgenic steroids in
primary rat hepatic cell cultures. Welder AA, Robertson JW, Melchert RB.
10. Arch Toxicol 1999 Nov;73(8-9):465-72, Evaluation of acute and chronic hepatotoxic effects exerted by
anabolic-androgenic steroid stanozolol in adult male rats. Boada LD, Zumbado M, Torres S, Lopez A,
Diaz-Chico BN, Cabrera JJ, Luzardo OP.
11. Clin J Sport Med 1999 Jan;9(1):34-9, Anabolic steroid-induced hepatotoxicity: is it overstated?
Dickerman RD, Pertusi RM, Zachariah NY, Dufour DR, McConathy WJ.
12. Int J Sports Med 1996 Aug;17(6):429-33, Body composition, cardiovascular risk factors and liver
function in long-term androgenic-anabolic steroids using bodybuilders three months after drug withdrawal.
Hartgens F, Kuipers H, Wijnen JA, Keizer HA.

