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786                       INDEX                                                                                                                                                                             INDEX




               Opsonization, 104, 106    Ortolani maneuver, 461     Otology, 533                hemoglobin, 665
                antibodies in, 112       Oseltamivir, 201           Ototoxicity                 toxicity, 210
                complement in, 106       Osgood-Schlatter disease, 461  aminoglycosides, 191, 204, 614  Oxygen-hemoglobin dissociation
                encapsulated organisms, 98  Osler nodes, 311          cisplatin/carboplatin, 442     curve, 666
               Optic disc                Osler-Weber-Rendu syndrome, 316  drug reaction and, 251  Oxytocin
                papilledema in, 538      Osmotic demyelination syndrome,   ethacrynic acid, 608  functions of, 328
               Optic nerve (CN II), 506         524                   loop diuretics, 608       hypothalamus production, 498
                embryologic derivation, 613  SIADH and, 338         Ouabain                     lactation and, 636
               Optic neuritis, 523       Osmotic diarrhea, 381        sodium-potassium pump and, 49  pituitary gland and, 327
               Optic neuropathy, 197     Osmotic laxatives, 401     Outcome (quality measurement),    signaling pathways for, 337
               Optochin                  Ossicles, 533                    273
                gram-positive antibiotic test, 134  conductive hearing loss and, 51  Outer membrane, 124  P
               Oral advance directives, 266  Ossification, 458      Outflow tract formation, 281  P-450, 197
               Oral contraceptives (OCPs)  Osteitis deformans, 463  Outpatient follow-up, 272  P2Y12 receptor
                hepatic adenomas and, 392  Osteitis fibrosa cystica, 345, 459, 464  “Oval fat bodies,” 594  inhibitors and, 437
                prolactin effects on, 330  Osteoarthritis, 466      Ovarian artery, 625         thrombogenesis and, 411
                reproductive hormones, 656  celecoxib for, 486      Ovarian cancer            P53 gene mutation
                SHBG effects on, 337       vs rheumatoid arthritis, 466  breastfeeding and, 636  dominant negative mutation, 56
                venous sinus thrombosis with, 503  Osteoarthropathy, hypertrophic  cisplatin/carboplatin for, 442  Pacemaker action potential, 292
               Oral glucose tolerance test, 346  cancer association, 228  epidemiology of, 643  Pacinian corpuscles, 494
               Oral hairy leukoplakia, 177  Osteoblastoma, 464        hypercalcemia and, 228  Paclitaxel, 441
               Oral/intestinal ganglioneuromatosis,   Osteoblasts, 459  irinotecan/topotecan for, 442  microtubules and, 48
                     351                   bone formation, 458        Lynch syndrome and, 388   targets of, 438
               Oral rehydration therapy, 146  cortisol effect on, 336  oncogenes and, 224     Paget disease
               Oral thrush, 177            Paget disease of bone, 463  paclitaxel for, 441      in breast, 650
               Orange body fluids, 196     teriparatide effect on, 487  Psammoma bodies in, 227  Paget disease (extramammary), 644
               Orchiectomy, 651          Osteochondroma, 464          tumor suppressor genes and, 224  Paget disease of bone, 463
               Orchiopexy, 651           Osteoclasts, 459           Ovarian cycle, 632          bisphosphonates, 486
               Orchitis, 170, 654          bisphosphonate effects, 486  Ovarian cysts, 646      lab values in, 464
               Orexigenic effect, 336      bone formation, 458      Ovarian ligament, 625       osteosarcomas and, 465
               Orexin, 568                 osteopetrosis, 463       Ovarian neoplasms           woven bone in, 458
                hypocretin receptor antagonist,   Paget disease of bone, 463  classification and characteristics,   Pain
                     Suvorexant as, 547  Osteodystrophy                   646                   with headaches, 518
               Organ failure, in acute pancreatitis,   renal, 345, 603  epithelial tumors, 646  loss in syringomyelia, 492
                     397                 Osteogenesis imperfecta      germ cell tumors, 647     post-stroke syndrome, 515
               Organic acidemias, 85       bisphosphonates, 486       sex cord stromal tumors, 647  receptors for, 494
               Organ of Corti, 533         collagen and, 50         Ovarian teratomas           spinal tracts for, 509
               Organogenesis               collagen synthesis and structure   paraneoplastic syndrome, 228  thalamic nuclei and, 498
                embryologic derivatives, 612, 613  in, 51           Ovaries                     treatment in multiple sclerosis,
                errors in, 613           Osteogenic sarcoma, 463, 465  anatomy of, 625               523
                fetal development, 612   Osteoma, 220, 464–465        descent of, 624           unilateral visual loss and, 523
                teratogens, 614            nomenclature for, 220      epithelial histology, 626  Pale (anemic) infarct, 210
               Organophosphates          Osteomalacia                 estrogen production, 630  Paliperidone, 573
                toxicity treatment, 248    hypophosphatemia, 591      lymphatic drainage, 624  Palivizumab, 122
               Organ transplants           lab values with rickets, 464  Overflow incontinence, 599  pneumonia prophylaxis, 169
                azathioprine for, 440      rickets, 463             Overuse injury            Pallor in aplastic anemia, 421
                cytomegalovirus, 186     Osteomyelitis, 180           elbow, 459              Palmar interossei, 450
                hairy leukoplakia and, 479  Pseudomonas aeruginosa, 143  knee, 461            Palmar reflex, 510
                kidneys, 580               sickle cell anemia, 422    radial nerve, 447       PALM-COEIN uterine bleeding
                WBC casts, 594             Staphylococcus aureus, 135  wrist, 459                    classification, 633
               Organum vasculosum of the lamina   Osteonecrosis, 463, 486  Ovotesticular disorder, 638  PALP, 653
                     terminalis (OVLT), 498  Osteopenia, 463        Ovulation                 Panacinar emphysema, 392, 674
               Orientation, 557          Osteopetrosis, 463, 464      anovulation causes, 645  p-ANCA
               Origin of replication, 38  Osteophytes, 466            progesterone and, 630     sclerosing cholangitis and, 395
               Orlistat, 400             Osteoporosis, 462            prolactin effect on, 330  ulcerative colitis, 382
                diarrhea, 249              bisphosphonates, 486       regulation of, 631      Pancoast tumor, 685
               Ornithine                   corticosteroids, 120     Ovulatory uterine bleeding, 633  lung cancer, 684
                cystinuria, 85             denosumab, 122           “Owl eyes” inclusions, 165, 429  superior vena cava syndrome, 685
                kidney stones and, 598     drug reaction and, 250   Oxacillin                   thoracic outlet syndrome, 448
                urea cycle, 82             estrogen, 459              characteristics of, 188  Pancreas
               Ornithine transcarbamylase, 74  Gaucher disease, 88  Oxaliplatin, 442            annular, 360
               Ornithine transcarbamylase   heparin, 436            Oxazepam, 546               biliary structures and, 368
                     deficiency, 61, 83    homocystinuria, 84       Oxazolidinones              blood supply and innervation of,
               Orotic acid, 83             hormone replacement therapy, 657  mechanism and use, 193  364
               Orotic aciduria, 420        lab values in, 464       Oxidative burst, 109        buds, 360
               “Orphan Annie” eyes (nuclei), 343  pituitary prolactinomas, 328  Oxidative phosphorylation, 78  divisum, 360
               Orthomyxoviruses, 168       raloxifene, 443, 656       metabolic site, 72        embryology, 360
                characteristics of, 167, 168  teriparatide for, 487   poisons, 78             Pancreatic cancer
                influenza viruses, 169     thiazides for, 609       Oxybutynin, 237, 241        5-fluorouracil for, 440
               Orthopedic conditions, 460  Osteosarcoma, 220, 464–465  Oxygen                   adenocarcinomas, 398
                lower extremity, 460, 461  Otitis media               deprivation, 669          biliary cirrhosis and, 395
               Orthopnea, 309              brain abscesses with, 180  in blood, 666             carcinogens causing, 225
               Orthostatic hypotension     Haemophilus influenzae, 128, 142  for carbon monoxide poisoning,   hyperbilirubinemia with, 393
                adrenal insufficiency, 349  Langerhans cell histiocytosis, 434  248             oncogenes and, 224
                α-blockers, 244            Streptococcus pneumoniae, 136  cluster headaches, 518  paraneoplastic syndromes with, 228
                phenoxybenzamine, 244      Wegener granulomatosis and, 315  exercise and, 670   tumor suppressor genes and, 224







          FAS1_2019_21_Index_749-806.indd   786                                                                        11/21/19   12:27 PM
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