Page 424 - fbkCardioDiabetes_2017

400 Cardio Diabetes Medicine 2017

Transcatheter Tricuspid Valve Repair/
Replacement
The current transcatheter approaches for treating TR
can be grouped by mechanism of action, including
annuloplasty systems, coaptation devices, leaflet de-
vices, caval valve implantation, and tricuspid valve re-
placement. All of the devices are in the early phases
of development in the TR space, and only one has
completed an early feasibility trial. Despite this, there
is significant excitement regarding the potential ben-
efits of these therapies.

Conclusion
Percutaneous devices have rapidly progressed from
closure of simple cardiac defects (ASD, VSD) to more
complex repair of cardiac valves. In some cases they
have begun to replace surgery as the initial means of
repair. With advances in transcatheter valves, surgery
may become obsolete.
References
1. Cribier A, Eltchaninoff H, Bash A, Borenstein N, Tron C, Bauer F, et al.
Percutaneous transcatheter implantation of an aortic valve prosthesis for
calcific aortic stenosis: first human case description. Circulation. 2002
Dec 10;106(24):3006–8.
2. Leon MB, Smith CR, Mack M, Miller DC, Moses JW, Svensson LG, et al.
Transcatheter Aortic-Valve Implantation for Aortic Stenosis in Patients Who
Cannot Undergo Surgery. N Engl J Med. 2010 Sep 22;363(17):1597–607.
3. Smith CR, Leon MB, Mack MJ, Miller DC, Moses JW, Svensson LG, et
al. Transcatheter versus Surgical Aortic-Valve Replacement in High-Risk
Patients. N Engl J Med. 2011 Jun 5;364(23):2187–98.
4. Leon MB, Smith CR, Mack MJ, Makkar RR, Svensson LG, Kodali SK, et al.
Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk
Patients. N Engl J Med. 2016 Apr 2;374(17):1609–20.
5. Thyregod HGH, Steinbrüchel DA, Ihlemann N, Nissen H, Kjeldsen BJ,
Petursson P, et al. Transcatheter Versus Surgical Aortic Valve Replacement
in Patients With Severe Aortic Valve Stenosis. J Am Coll Cardiol. 2015
May 26;65(20):2184.
6. Feldman T, Foster E, Glower DD, Kar S, Rinaldi MJ, Fail PS, et al. Percu-
taneous Repair or Surgery for Mitral Regurgitation. N Engl J Med. 2011
Apr 4;364(15):1395–406.
7. Cheung A, Webb JG, Barbanti M, Freeman M, Binder RK, Thompson C,
et al. 5-Year Experience With Transcatheter Transapical Mitral Valve-in-
Valve Implantation for Bioprosthetic Valve Dysfunction. J Am Coll Cardiol.
2013 Apr 30;61(17):1759.
8. McElhinney DB, Hellenbrand WE, Zahn EM, Jones TK, Cheatham JP,
Lock JE, et al. Short- and medium-term outcomes after transcatheter
pulmonary valve placement in the expanded multicenter US melody valve
trial. Circulation. 2010 Aug 3;122(5):507–

GCDC 2017