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CHAPTER 30: Interventional Radiology  209



                     CHAPTER    Interventional Radiology                  and may poorly tolerate attempts to initiate therapy at bedside. Clearly,
                                                                          there are exceptions and the risks and benefits of any therapy are dic-
                      30        Brian Funaki                              tated by local expertise and must be carefully considered and discussed
                                                                          among the ICU team and IR team.
                                Jonathan M. Lorenz
                                Rakesh Navuluri                           PREPROCEDURAL PREPARATION
                                Thuong G. Van Ha
                                Steven M. Zangan                          It is especially important for critically ill patients to be properly prepared
                                                                          for IR therapy. If patients are obtunded or combative and will be unable
                                                                          to lie still, a consultation with an anesthesiologist is strongly recom-
                     KEY POINTS                                           mended. When possible, coagulopathies should be corrected. When this
                                                                          is not possible, procedures should be delayed or modified. For example,
                        • Interventional radiology (IR) provides a gamut of minimally inva-  an arterial sheath may be left in place after completion of angiography to
                      sive therapies well suited for the critical care patient population.  be removed later. Heparin should be discontinued at least 2 hours prior
                       • The dictum of “smaller, faster, safer, better” is the ideal of minimally   to procedures and restarted 6 to 8 hours after completion of procedures
                      invasive image-guided therapy. In the appropriate patient, this type of   as a drip (no bolus). If the patient is allergic to contrast, preprocedural
                      therapy is invariably better tolerated than more invasive techniques.  medications should be given whenever possible.
                        • Three primary image modalities are used to guide IR procedures:   Acceptable guidelines will vary slightly from institution to institution
                      fluoroscopy, computed tomography (CT), and ultrasound (US).   but general guidelines for patients to undergo IR therapy are
                      Increasingly, hybrid suites are equipped with all three modalities    • International normalized ratio <2.0
                        • Appropriate ICU-monitoring devices and support personnel must     • Platelets >75,000
                      be available in the IR suite to best serve the critical care population.
                                                                            • Contrast allergy premedication: methylprednisolone 32 mg, 12 and
                                                                            2 hours prior to contrast administration, diphenhydramine 50 mg, 1 hour
                                                                            before contrast administration (ACR Manual on Contrast Media, 2010)
                    Interventional radiology (IR) is a field of medicine devoted to using
                    image-guided  minimally  invasive  techniques  to  improve  patient  care.   If the patient has renal insufficiency, this should be discussed with the
                    Rather than being unified by an organ system or disease, interventional   interventional radiologist because iodinated contrast material is nephro-
                    radiologists are guided by the dictum of “smaller, faster, safer, better”   toxic and should be avoided unless absolutely necessary. In many cases,
                    therapy. As such, the interventional radiologist treats patients of all demo-  alternative contrast agents such as carbon dioxide may be used to facilitate
                    graphics. Commonly, IR procedures are performed instead of traditional   therapy. Carbon dioxide enhancement may be used to guide inferior vena
                    open surgical procedures because minimally invasive procedures are often   cava (IVC) filter insertion, transjugular intrahepatic shunt creation, and to
                    better tolerated with less morbidity and lower mortality. This is particu-  perform diagnostic angiography below the chest. In the past, gadolinium
                    larly important in critical care patients who often have significant comor-  was used in patients with renal insufficiency. Currently, due to the associated
                    bidities. The overwhelming majority of procedures offered in the IR suite   risk of nephrogenic systemic sclerosis, this practice has been discontinued.
                    are performed using conscious sedation, which also tends to limit risks
                    associated with these therapies. As such, it is critical that patients be able  PATIENT MONITORING IN IR
                    to minimally cooperate with interventional radiologists. If patients are   While the level of monitoring equipment and specialized staff varies
                    combative or unable to lie still, anesthesiologists may be required to assist.
                                                                          from institution to institution, in general, all state-of-the-art IR suites
                                                                          are outfitted with basic patient monitoring equipment including elec-
                    WHERE SHOULD THERAPY BE PERFORMED?                    trocardiography, noninvasive pulse oximetry, and automated blood

                    Provided appropriate personnel and monitoring devices are available,   pressure monitoring. Wall suction and oxygen are also ubiquitous and
                    as a general rule, the safest and best place to perform an IR procedure   newer rooms can monitor end-tidal carbon dioxide, which can detect
                    is unquestionably in the IR suite. Some very straightforward procedures   respiratory depression sooner than pulse oximetry. Every IR suite is
                    such as drainage of a large, superficial abscess can be done at bedside   staffed with at least one technologist and one nurse in addition to the
                    but there are significant disadvantages to initiating IR therapy in the   physician(s) providing therapy. In our hospital, the majority of our IR
                    ICU. First, the safety and effectiveness of nearly all IR procedures are   nurses have ICU experience; during procedures, they administer seda-
                    predicated on high-quality imaging. In many procedures, more than one   tion (typically midazolam and fentanyl) and monitor the patient.
                    imaging modality is used in an IR suite to provide the largest margin of   Critically ill patients from the ICU should be accompanied to IR
                    safety. For example, when cholecystostomy is performed in the IR suite,   with equipment and staff that can handle any additional life supportive
                    the gallbladder is punctured using ultrasound (US) guidance and the   measures. In the authors’ opinion, patients are best served if a physician
                    remainder of the procedure is completed using fluoroscopic guidance.   from the ICU also accompanies the patient to the IR suite. In a very
                    While it is possible to perform the procedure using only US guidance at   practical sense, it is impossible for an interventional radiologist to both
                    bedside, sonographic visualization of needles, wires, dilators, and tubes   competently perform an image-guided procedure while simultaneously
                    may be limited, particularly in large patients. Portable fluoroscopy units   directing supportive therapy in a critically ill patient unfamiliar to him
                    are typically inadequate because they are awkward, have a small field of   or her. Optimal patient care dictates constant communication and close
                    view, and provide no meaningful radiation shielding. Second, and more   cooperation between the ICU and IR services throughout this process.
                    importantly, an interventional radiologist has a limited ability to recog-
                    nize and treat any complication that occurs during a bedside procedure.  PERCUTANEOUS ABSCESS DRAINAGE
                    Complications that may prove lethal at bedside may be easily handled in
                    an IR suite given the superior imaging and immediate access to special-  KEY POINTS
                    ized catheters and other equipment. One common dilemma involves the
                    patient who needs an IR therapy but is “too unstable” to travel to the IR     • Percutaneous  abscess  drainage  is  the  treatment  of  choice  for
                    suite. In our collective experience, as a rule of thumb, patients that are   infected, well-defined fluid collections.
                    too unstable to travel are usually also too unstable to undergo IR therapy









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