Page 561 - Clinical Application of Mechanical Ventilation
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Weaning from Mechanical Ventilation  527


                        WEANING PROCEDURE



                                             The spontaneous breathing trial (SBT) is the major diagnostic test to deter-
                        spontaneous breathing trial
                        (SBT): An evaluation of a   mine if patients can be successfully extubated and weaned from mechanical ven-
                        patient’s readiness for weaning   tilation. Low level pressure support (PS), continuous positive airway pressure
                        from mechanical ventilation and
                        extubation. Spontaneous breath-  (CPAP), or automatic tube compensation (ATC) may be used along with SBT
                        ing may be augmented with    to augment a patient’s spontaneous breathing efforts (Keenan, 2002). Based on
                        low-level (#8 cm H 2 O) of pres-
                        sure support, CPAP, or automatic   the results of the sixth International Consensus Conference on Intensive Care
                        tube compensation (ATC). SBT   Medicine, synchronized intermittent mandatory ventilation (SIMV) should
                        may last up to 30 minutes.
                                             be avoided as a stand-alone weaning modality (Boles et al., 2007). However,
                                             SIMV remains an effective tool in providing partial ventilatory support during
                        synchronized intermittent   continuous mechanical ventilation.
                        mandatory ventilation (SIMV):
                        A mode of ventilation that permits
                        spontaneous breaths between   Spontaneous Breathing Trial
                        ventilator breaths. The ventilator
                        breaths are synchronized (manda-
                        tory breaths that may come   Once a decision is made to proceed with weaning, the patient may be discontinued
                        slightly sooner or later) to coincide
                        with the patient’s inspiratory   from full ventilatory support and placed on a spontaneous breathing mode via the ven-
                        efforts.
                                             tilator or T-tube (Brigg’s adaptor) for up to 30 minutes. Oxygen and low level pressure
                                             support may be used to supplement oxygenation and augment spontaneous breathing.
                                               The criteria for passing an SBT include normal respiratory pattern (i.e., absence
                                             of rapid shallow breathing), adequate gas exchange, and hemodynamic stability.
                                             The results of six studies show that only 13% of patients who successfully passed the
                                             SBT and were extubated required reintubation (Boles et al., 2007).
                                               There is no difference in terms of successful SBT among patients undergoing
                                             stand-alone SBT, SBT with low level of pressure support, and SBT with CPAP
                                             or automatic tube compensation (Boles et al., 2007). Since patients who fail the
                                             SBT do so within the first 20 to 30 minutes of SBT, there is no need to use an ex-
                                             tended SBT (e.g.,120-min trial) (Yang et al., 1991; Perren et al., 2002). Table 16-4
                                             describes the procedure for the spontaneous breathing trial and other partial ven-
                                             tilatory support procedures. Note that SIMV is used to provide partial ventilatory
                                             support and it is not recommended as a stand-alone weaning modality.


                                             Failure of SBT


                                             Patients who fail the SBT often do so within the first 20 to 30 minutes of the trial.
                                             They also exhibit the following clinical signs and symptoms: agitation and anxiety,
                                             diminished mental status, diaphoresis, cyanosis, and evidence of increased work of
                                             breathing (Boles et al., 2007). Clinical data that correlate with failure of SBT are
                                             summarized in Table 16-5.

                                             Pressure Support Ventilation


                                             Pressure support ventilation (PSV) or similar adjuncts (e.g., proportional pressure
                                             support, volume-assured pressure support) may be applied during weaning. PSV






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