Page 564 - Clinical Application of Mechanical Ventilation
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530    Chapter 16


                                            circumstances, there are other modes of ventilation that provide partial ventilatory
                                            support (MacIntyre et al., 2001). These modes are volume support, volume-assured
                                            pressure support, mandatory minute ventilation, and airway pressure-release venti-
                                            lation. For a more detailed discussion on these modes, refer to Chapter 4, Operating
                                            Modes of Mechanical Ventilation.
                                             Volume support (VS) and volume-assured pressure support (VAPS) are a form
                                            of PSV that “guarantees” a preset tidal volume. In VS, the pressure support level
                                            is adjusted automatically to achieve the target tidal volume. In VAPS, it guaran-
                                            tees a preset tidal volume by incorporating inspiratory pressure support ventila-
                                            tion (PSV) with conventional volume-assisted cycles (VAV). Unlike typical PSV,
                                            VAPS assures stable tidal volume in patients with irregular breathing patterns. By
                                            decreasing the frequency, the work of breathing is shifted from the ventilator to
                                            the patient.
                                             Mandatory minute ventilation (MMV) is a form of SIMV in which the min-
                                            ute ventilation is guaranteed. The ventilator adjusts the frequency automatically to
                                            achieve the target minute ventilation. By decreasing the MMV level, the patient
                                            assumes more spontaneous breathing.
                                             Airway pressure-release ventilation (APRV) has two pressure levels: the higher
                                            airway pressure (e.g., 10 cm H O) and the lower release pressure (usually 0 cm
                                                                       2
                                            H O).  The  tidal  volume  is  determined  by  the  pressure  gradient  between  the
                                             2
                                            airway  pressure  and  the  release  pressure.  In  APRV,  exhalation  occurs  during
                                            pressure release and inhalation occurs when the pressure returns to the airway
                                            pressure. Weaning may be done by decreasing the frequency of pressure release.
                                            When the frequency of pressure release is zero, the patient is essentially on a
                                            CPAP mode.



                      WEANING PROTOCOL



                                            Weaning  protocol  and  clinical  practice  guidelines  for  weaning  are  primarily
                                            used to outline the standard of care for the purpose of weaning from mechanical
                                            ventilation. In general, they often include three elements: the patient condition in
                                            which weaning may be attempted, the detailed process of weaning, and the evalu-
                                            ation of weaning outcomes.
                                             There are many weaning protocols published in the literatures or developed
                                            by individual hospitals or departments. Each of them can be useful when the
                                            elements of weaning are incorporated with sound clinical reasoning and imple-
                                            mentation. The criteria in the weaning protocol should be used as guidelines
                                            only and must not be carried out using a “cookbook” approach. Individual pa-
                                            tient  differences  must  also  be  considered  since  disease  processes  and  patient
                                            characteristics are two of many variables that may affect the outcomes of a wean-
                                            ing protocol (Keenan, 2002). Weaning protocols range from simple to com-
                                            plex. Table 16-6 provides a simple weaning protocol for mechanical ventilation
                                            (Grap et al., 2003).








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