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Effects of Positive Pressure Ventilation  29



                          TABLE 2-2  Relationship of Inspiratory Pressure (P I ) and Alveolar Pressure (P ALV ) during Positive Pressure
                                    Ventilation

                          Positive
                          Pressure
                          Ventilation           P  (cm H O)        P ALV  (cm H O)       ∆P         FLOW
                                                        2
                                                                             2
                                                  I
                          Inspiration                20                  0              120          Into lungs
                          End-inspiration            20                 20                    0      No flow

                          Expiration                 0                  20              220          Out of lungs

                          End-expiration             0                   0                    0      No flow
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                                             pressure ventilation. The pressure readings in Table 2-2 are for illustration purposes
                                             only. The barometric pressure is assigned 0 cm H O for easy comparison of pressure
                                                                                      2
                                             changes during positive pressure ventilation.
                                               Under normal conditions, the pressure gradient and  tidal volume are  directly
                                             related. During pressure-controlled ventilation, a higher peak inspiratory pressure
                                             typically results in a larger tidal volume. However, there are some exceptions to this
                                             relationship. (Table 2-3).

                                             Airway Pressures


                                             During pressure-controlled ventilation, the  peak inspiratory pressure (PIP) is
                        peak inspiratory pressure
                        (PIP): Maximum pressure mea-  preset according to the estimated tidal volume requirement of a patient. The inspi-
                        sured during one respiratory cycle,   ratory phase terminates once the preset pressure is reached. For this reason, the pa-
                        usually at  end-inspiration.
                                             tient may receive a smaller volume when the preset pressure is reached prematurely,
                                             as would happen under conditions of low compliance or high airway resistance.
                                               During volume-controlled ventilation, the tidal volume is preset and the pres-
                                             sure used by the ventilator to deliver this preset volume is variable. The PIP at



                                                TABLE 2-3 Conditions That Limit the Volume Delivered by Positive Pressure Ventilation


                                                Conditions                             Examples
                                                Peak inspiratory pressure reached      Airway obstruction
                                                  too soon                             Kinking of ET tube
                                                                                       Bronchospasm
                                                                                       Low lung compliance
                                                                                       Pressure limit set too low
                                                Unable to reach peak inspiratory       ET tube cuff leak
                                                  pressure                             Ventilator circuit leak
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