Page 185 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)
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A.  Causes and Consequences of Liver Failure

                     Inflammations
                     (viral hepatitis,
                     cholangitis, etc.)
                Toxins
                (e.g. organic         Alcohol  Venous congestion
                nutrients)                    (e.g. in right heart
                                              failure)

                                                        Various inherited
                                                        diseases
             Phalloidin,
             amanitin
                                                                       Liver Failure
                                      Chronic
                       Acute

                                                                       Plate 6.21
                                     Cirrhosis


                               Liver failure


                Hypo-     Portal   Cholestasis
                albuminemia  hypertension
                                                   +    –
                                                 NH 4  + HCO 3
                                     Fat
                                   absorption
                                                H 2 N  NH 2
                              Varices  Vitamin K
                                   deficiency      C
                                                   O
                        Exudative                 Urea
                Ascites  enteropathy  Clotting factors
                                                         Aromatic
               Hyperaldo-                                amino acids
               steronism     Gastrointestinal bleeding
                           Enteric amino
               Hypokalemia  acid breakdown
                                                ‘False transmitters’
                     +       Hyper-
               Renal NH 4
               production  ammoniemia

                                       Hyper-
                          Alkalosis   ventilation  Encephalopathy     175

       Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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