Page 349 - Color Atlas Of Pathophysiology (S Silbernagl Et Al, Thieme 2000)

A. Epilepsy
Fever Injuries Genetic defects Tumors, Poisoning
(scars) bleeding, (alcohol),
Lack of sleep abscess inflammation
Hypoxia Cell swelling
Paroxysmal activation
2+
of Ca channels K +
1 ECS Cl –

Na + Ca 2+
AMPA etc.
Na + Ca 2+ Repolarization
etc.
Glutamate 3 Depolarization Mg 2+ K + Epilepsy
Depola- 2
Mg 2+ rization
NMDA
Ca 2+ Plate 10.21
Inhibitory
basket cell 2+ K +
Na + Pyramidal Ca
cell
4
ATP 5 Glutamate
GD Vitamin B 6
K + O 2 GABA

Cl –
K +

Generalized seizures

Localized seizures
(e.g. Jacksonian epilepsy) Unconsciousness
Hyperactivity
Motor
(fits)
Sensory
(hallucinations) Autonomic Cognitive Emotional 339
(salivation) (‘déjà vu’) (rage, laughter)

Silbernagl/Lang, Color Atlas of Pathophysiology © 2000 Thieme
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