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298  P R I N C I P L E S   A N D   P R A C T I C E   O F   C R I T I C A L   C A R E

         Ventilatory Support                                  ●  pulmonary hypertension from cardiac failure or valve
         Ventilation  should  be  approached  according  to  the   disease
         general principles described in Chapter 15. As anaesthe-  ●  cardiogenic shock/post-pump failure
         sia is not typically reversed at the end of the operation,   ●  systemic inflammatory response syndrome due to car-
         patients are generally admitted apnoeic, and within 1–3   diopulmonary bypass
         hours return to wakefulness and spontaneous breathing.  ●  early or rapid weaning that is undertaken before com-
                                                                 plete readiness, leading to failure at weaning attempt
         Ensuring a secure airway is an initial priority; the follow-  ●  surgical pain limiting spontaneous effort and poten-
         ing should be undertaken:                               tially leading to atelectasis or sputum retention.
         ●  Confirmation  of  endotracheal  tube  position  and  its
            security immediately on admission:                Approaches to weaning
            ●  auscultation for equal bilateral air entry to rule out   As patients often have no underlying pulmonary pathol-
               right main bronchus intubation,                ogy, and have been ventilated for brief periods only, rapid
            ●  recording  of  the  ETT  insertion  length  should  be   weaning phases have become the norm in most centres.
               sufficient                                     In  many  instances,  as  soon  as  the  patient  wakes  and
            ●  postoperative chest X-ray, taken within 30 minutes,   begins  spontaneous  breathing  activity  he/she  may  be
               should also be examined for ETT positioning    suitable for at least a trial of spontaneous breathing in
         ●  Initial ETT care:                                 CPAP mode, usually with some modest level of pressure
            ●  assessment for air leak around the cuff (via perfor-  support (e.g. 5–10 cm H 2O). If tolerated and the patient
               mance  of  minimal  occlusive  volume  or  pressure   maintains an adequate minute volume, SpO 2  and PaCO 2 ,
               tests)                                         then  extubation  may  be  considered  within  as  little  as
            ●  ETT is adequately secured and positioned so as not   another  30  minutes.  Normal  demonstrations  of  airway
               to apply undue pressure against soft tissues of the   protection  capability  (e.g.  neuromuscular  control,  gag,
               mouth and lips.                                swallow, cough and patient strength) should be sought
         There has been a general trend to more rapid ventilatory   before extubation (see Chapter 15 for details).
         weaning in recent years, and in some centres ‘fast-track’   These short ventilation times and rapid weaning carry a
         cardiac surgical recovery includes extubation at the end   greater risk of weaning failure. Patients may initially wake
         of  the  operation  before  transfer  to  a  recovery  unit  for   and  appear  to  sustain  spontaneous  ventilation  well  for
         suitable patients. Indices of respiration show no improve-  some  time,  only  to  lapse  back  under  anaesthetic  influ-
         ment  when  intubation  is  maintained  for  longer  com-  ence.  A  return  to  greater  ventilatory  support  may  be
                                   30
         pared  with  early  extubation,   and  pooled  results  from   necessary. Additionally, demonstrations of spontaneous
         randomised early extubation trials show earlier ICU dis-  breathing for as little as 30 minutes may be insufficient
         charge and shorter lengths of stay (by 1 day) when early   for  patients  to  fail,  as  they  have  not  exceeded  reserves.
         extubation is undertaken. 31                         Failure to wean carries greater significance in the cardiac
         Apart  from  these  fast-track  approaches,  ventilation  is   surgical patient with existing pulmonary hypertension, as
         commonly employed for 2–6 hours in the uncomplicated   respiratory  acidosis  causes  pulmonary  vasoconstriction,
         patient. Reasons for continuing ventilation beyond this   abruptly worsening pulmonary hypertension and the risk
         time frame may include:                              of pulmonary oedema and/or right ventricular failure.
         ●  intraoperative neurological event                 Where  ventilation  has  been  more  prolonged  due  to
         ●  gas exchange deficit with unresolved hypoxaemia   postoperative  pulmonary  problems,  weaning  may  be
         ●  ventilatory inadequacy                            approached more cautiously, as might be applied to the
         ●  significant haemodynamic insufficiency            general longer-term ventilated patient. Gradual manda-
         ●  patients  returning  from  theatre  late  in  the  evening   tory rate reduction or increasing periods of spontaneous
            may  sometimes  continue  ventilation  overnight  to   ventilation interspersed with periods of greater assistance
            optimise postextubation breathing ability.        have been used. 31
         For  many  patients,  ventilation  is  provided  purely  for
         initial airway and apnoea protection rather than for treat-  Assessment and Management of
         ment of pulmonary deficits. In the absence of pulmonary   Postoperative Bleeding
         disease, many centres provide fairly uniform approaches   The harvest sites for radial arteries or saphenous veins are
         to parameter settings that aim at sustaining ventilation   uncommon sources of significant blood loss and are gen-
         and  oxygenation,  while  limiting  traumatic  risk  to  the   erally  easily  managed  with  dressings  or  compression.
         lungs (see Table 12.1). However, approaches to ventila-  Intrathoracic  bleeding,  however,  may  be  torrential  and
         tion will need to be tailored in the presence of operative   threaten  life.  Occasionally  surgical  bleeding  from  the
         complications or coexisting lung disease.            aorta,  arterial  grafts  or  myomectomy  sites  may  exceed
                                                              replacement capabilities, and at times patients succumb
         Ventilation challenges specific to the postcardiac surgical   to  overwhelming  haemorrhage.  Maintenance  of  drain
         setting include:
                                                              patency  and  strict  recording  of  losses  and  total  fluid
         ●  atelectasis due to operative access               balance  are  paramount,  and  fluid  balance  assessments
         ●  pneumothorax  (pleural  opening  for  grafts,  or   over shorter intervals, even every 5–10 minutes, become
            ventilation-induced trauma)                       necessary during active bleeding. Because of the potential
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