Page 503 - Concise Pathology for Exam Preparation ( PDFDrive )

488 SECTION II Diseases of Organ Systems

• High-grade papillary urothelial carcinomas show marked atypia and increased mito-
ses including atypical ones. They have a disorderly architecture and show loss of
nuclear polarity and dyscohesiveness. They have major potential for recurrence and
metastases.

Clinical Features
Painless haematuria, frequency, urgency and dysuria

Complications

Stricture formation, hydronephrosis and pyonephrosis
Prognosis

Depends on tumour grade or blood group antigens (tumour cells expressing A, B and H
antigens have a better prognosis)

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