Page 1812 - Hematology_ Basic Principles and Practice ( PDFDrive )

1616 Part X Transplantation

Disease stage remains a strong predictor of overall transplant outcome, Lee SJ, Klein J, Haagenson M, et al: High-resolution donor-recipient HLA
and expediency in timing of transplantation for patients with high- matching contributes to the success of unrelated donor marrow transplan-
risk disease is paramount. New research avenues include identification tation. Blood 110:4576, 2007.
of novel MHC resident genetic variation that may contribute to risks Morishima S, Ogawa S, Matsubara A, et al: Impact of highly conserved HLA
of GVHD and TRM and the precise role of HLA region variation haplotype on acute graft-versus-host disease. Blood 115:4664, 2010.
in preventing transplant complications and disease relapse. Morishima Y, Yabe T, Matsuo K, et al: Effects of HLA allele and killer
immunoglobulin-like receptor ligand matching on clinical outcome in
leukemia patients undergoing transplantation with T-cell-replete marrow
SUGGESTED READINGS from an unrelated donor. Biol Blood Marrow Transplant 13:315, 2007.
Petersdorf E, Gooley TA, Malkki M, et al: HLA-C expression levels define
Anasetti C, Logan BR, Lee SL, et al: Peripheral-blood stem cells versus permissible mismatches in hematopoietic cell transplantation. Blood
bone marrow from unrelated donors. N Engl J Med 367:1487–1496, 124:3996–4003, 2014.
2012. Petersdorf EW, Malkki M, Gooley TA, et al: MHC haplotype matching for
Fernandez-Vina MA, Klein JP, Haagenson M, et al: Multiple mismatches unrelated hematopoietic cell transplantation. PLoS Med 4:e8, 2007.
at the low expression HLA loci DP, DQ, and DRB3/4/5 associate with Petersdorf EW, Malkki M, Horowitz MM, et al: Mapping MHC haplotype
adverse outcomes in hematopoietic stem cell transplantation. Blood effects in unrelated donor hematopoietic cell transplantation. Blood
121:4603–4610, 2013. 121:1896–1905, 2013.
Fleischhauer K, Shaw BE, Gooley T, et al: Effect of T-cell-epitope match- Petersdorf EW, Malkki M, O’hUigin C, et al: High HLA-DP expression and
ing at HLA-DPB1 in recipients of unrelated-donor haemopoietic-cell graft-versus-host disease. N Engl J Med 373:599–609, 2015.
transplantation: a retrospective study. [Erratum appears in Lancet Oncol. Pidala J, Kim J, Schell M, et al: Race/ethnicity affects the probability of
2012 Apr;13(4):e134-5]. Lancet Oncol 13:366–374, 2012. finding an HLA-A,B,C, and DRB1 allele-matched unrelated donor and
Foeken LM, Green A, Hurley CK, et al: Monitoring the international use of likelihood of subsequent transplant utilization. Bone Marrow Transplant
unrelated donors for transplantation: the WMDA annual reports. Bone 48:346–350, 2013.
Marrow Transplant 45:811, 2010. Pidala J, Sarwal M, Roedder S, et al: Biologic markers of chronic GVHD.
Gragert L, Eapen M, Williams E, et al: HLA match likelihoods for hemato- Bone Marrow Transplant 2013. [Epub ahead of print].
poietic stem-cell grafts in the US registry. N Engl J Med 371:339–348, Woolfrey A, Klein JP, Haagenson M, et al: HLA-C antigen mismatch is
2014. associated with worse outcome in unrelated donor peripheral blood stem
Hurley CK, Woolfrey A, Wang T, et al: The impact of HLA unidirectional cell transplantation. Biol Blood Marrow Transplant 17:885, 2011.
mismatches on the outcome of myeloablative hematopoietic stem cell
transplantation with unrelated donors. Blood 121:4800–4806, 2013.
Kawase T, Matsuo K, Kashiwase K, et al: HLA mismatch combinations REFERENCES
associated with decreased risk of relapse: implications for the molecular
mechanism. Blood 113:2851, 2009. For the complete list of references, log on to www.expertconsult.com.