Page 317 - Hematology_ Basic Principles and Practice ( PDFDrive )
P. 317
Chapter 23 Dendritic Cell Biology 260.e5
180. Green EA, Eynon EE, Flavell RA: Local expression of TNFα in neo- patients. Proc Natl Acad Sci USA 103:7000–7005, 2006. doi: 10.1073/
natal NOD mice promotes diabetes by enhancing presentation of islet pnas.0600363103.
+
antigens. Immunity 9:733–743, 1998. 202. Ruffell B, et al: Macrophage IL-10 blocks CD8 T cell-dependent
181. Marshak-Rothstein A: Toll-like receptors in systemic autoimmune responses to chemotherapy by suppressing IL-12 expression in intratu-
disease. Nat Rev Immunol 6:823–835, 2006. doi: 10.1038/nri1957. moral dendritic cells. Cancer Cell 26:623–637, 2014. doi: 10.1016/j.
182. Lebre MC, et al: Rheumatoid arthritis synovium contains two subsets ccell.2014.09.006.
of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles. Am 203. Godefroy E, et al: Matrix metalloproteinase-2 conditions human
J Pathol 172:940–950, 2008. doi: 10.2353/ajpath.2008.070703. dendritic cells to prime inflammatory T(H)2 cells via an IL-12- and
183. Leung BP, et al: A novel dendritic cell-induced model of erosive inflam- OX40L-dependent pathway. Cancer Cell 19:333–346, 2011. doi:
matory arthritis: distinct roles for dendritic cells in T cell activation and 10.1016/j.ccr.2011.01.037.
induction of local inflammation. J Immunol 169:7071–7077, 2002. 204. Godefroy E, et al: Activation of toll-like receptor-2 by endogenous
doi: 10.4049/jimmunol.169.12.7071. matrix metalloproteinase-2 modulates dendritic-cell-mediated inflam-
184. Benham H, et al: Citrullinated peptide dendritic cell immunotherapy matory responses. Cell Rep 9:1856–1870, 2014. doi: 10.1016/j.
in HLA risk genotype-positive rheumatoid arthritis patients. Sci Transl celrep.2014.10.067.
Med 7:290ra287, 2015. doi: 10.1126/scitranslmed.aaa9301. 205. Spranger S, Bao R, Gajewski TF: Melanoma-intrinsic β-catenin signal-
185. Maloy KJ, Powrie F: Intestinal homeostasis and its breakdown in ling prevents anti-tumour immunity. Nature 523:231–235, 2015. doi:
inflammatory bowel disease. Nature 474:298–306, 2011. doi: 10.1038/ 10.1038/nature14404.
nature10208. 206. Broz ML, et al: Dissecting the tumor myeloid compartment reveals rare
186. Fonseca DM, et al: microbiota-dependent sequelae of acute infection activating antigen-presenting cells critical for T cell immunity. Cancer
compromise tissue-specific immunity. Cell 163:354–366, 2015. doi: Cell 26:638–652, 2014. doi: 10.1016/j.ccell.2014.09.007.
10.1016/j.cell.2015.08.030. 207. Bonifaz LC, et al: In vivo targeting of antigens to maturing dendritic
187. Greter M, et al: Dendritic cells permit immune invasion of the CNS cells via the DEC-205 receptor improves T cell vaccination. J Exp Med
in an animal model of multiple sclerosis. Nat Med 11:328–334, 2005. 199:815–824, 2004. doi: 10.1084/jem.20032220.
doi: 10.1038/nm1197. 208. Dhodapkar MV, et al: Induction of antigen-specific immunity with a
188. Anandasabapathy N, et al: Flt3L controls the development of radio- vaccine targeting NY-ESO-1 to the dendritic cell receptor DEC-205.
sensitive dendritic cells in the meninges and choroid plexus of the Sci Transl Med 6:232ra251, 2014. doi: 10.1126/scitranslmed.3008068.
steady-state mouse brain. J Exp Med 208:1695–1705, 2011. doi: 209. Mellman I, Coukos G, Dranoff G: Cancer immunotherapy comes of
10.1084/jem.20102657. age. Nature 480:480–489, 2011. doi: 10.1038/nature10673.
189. Yogev N, et al: Dendritic cells ameliorate autoimmunity in the CNS 210. Levy B, Panicalli D, Marshall J: TRICOM: enhanced vaccines
+
by controlling the homeostasis of PD-1 receptor regulatory T cells. as anticancer therapy. Expert Rev Vaccines 3:397–402, 2004. doi:
Immunity 37:264–275, 2012. doi: 10.1016/j.immuni.2012.05.025. 10.1586/14760584.3.4.397.
190. Isaksson M, Lundgren BA, Ahlgren KM, et al: Conditional DC deple- 211. Kantoff PW, et al: Sipuleucel-T immunotherapy for castration-resistant
tion does not affect priming of encephalitogenic Th cells in EAE. Eur prostate cancer. N Engl J Med 363:411–422, 2010. doi: 10.1056/
J Immunol 42:2555–2563, 2012. doi: 10.1002/eji.201142239. NEJMoa1001294.
191. Saxena V, Ondr JK, Magnusen AF, et al: The countervailing actions of 212. Constantino J, Gomes C, Falcao A, et al: Antitumor dendritic cell-based
myeloid and plasmacytoid dendritic cells control autoimmune diabetes vaccines: lessons from 20 years of clinical trials and future perspectives.
in the nonobese diabetic mouse. J Immunol 179:5041–5053, 2007. doi: Transl Res 2015. doi: 10.1016/j.trsl.2015.07.008.
10.4049/jimmunol.179.8.5041. 213. Wilgenhof S, et al: Long-term clinical outcome of melanoma patients
192. Calderon B, Suri A, Miller MJ, et al: Dendritic cells in islets of Langer- treated with messenger RNA-electroporated dendritic cell therapy fol-
hans constitutively present β cell-derived peptides bound to their class lowing complete resection of metastases. Cancer Immunol Immunother
II MHC molecules. Proc Natl Acad Sci USA 105:6121–6126, 2008. 64:381–388, 2015. doi: 10.1007/s00262-014-1642-8.
doi: 10.1073/pnas.0801973105. 214. Bol KF, et al: Intranodal vaccination with mRNA-optimized dendritic
+
193. Grupillo M, et al: Essential roles of insulin expression in Aire cells in metastatic melanoma patients. Oncoimmunology 4:e1019197,
tolerogenic dendritic cells in maintaining peripheral self-tolerance 2015. doi: 10.1080/2162402X.2015.1019197.
of islet β-cells. Cell Immunol 273:115–123, 2012. doi: 10.1016/j. 215. Mitchell DA, et al: Tetanus toxoid and CCL3 improve dendritic cell
cellimm.2011.12.010. vaccines in mice and glioblastoma patients. Nature 519:366–369,
194. Andrews DM, Andoniou CE, Granucci F, et al: Infection of dendritic 2015. doi: 10.1038/nature14320.
cells by murine cytomegalovirus induces functional paralysis. Nat 216. Ali OA, Huebsch N, Cao L, et al: Infection-mimicking materials to
Immunol 2:1077–1084, 2001. doi: 10.1038/ni724. program dendritic cells in situ. Nat Mater 8:151–158, 2009. doi:
195. White TE, et al: The retroviral restriction ability of SAMHD1, but 10.1038/nmat2357.
not its deoxynucleotide triphosphohydrolase activity, is regulated by 217. Fracol M, et al: Response to HER-2 pulsed DC1 vaccines is predicted
phosphorylation. Cell Host Microbe 13:441–451, 2013. doi: 10.1016/j. by both HER-2 and estrogen receptor expression in DCIS. Ann Surg
chom.2013.03.005. Oncol 20:3233–3239, 2013. doi: 10.1245/s10434-013-3119-y.
196. Gao D, et al: Cyclic GMP-AMP synthase is an innate immune sensor of 218. Valmori D, et al: Vaccination with NY-ESO-1 protein and CpG in
HIV and other retroviruses. Science 341:903–906, 2013. doi: 10.1126/ Montanide induces integrated antibody/Th1 responses and CD8 T cells
science.1240933. through cross-priming. Proc Natl Acad Sci USA 104:8947–8952, 2007.
197. Yoh SM, et al: PQBP1 is a proximal sensor of the cGAS-dependent doi: 10.1073/pnas.0703395104.
innate response to HIV-1. Cell 161:1293–1305, 2015. doi: 10.1016/j. 219. Brody JD, et al: In situ vaccination with a TLR9 agonist induces systemic
cell.2015.04.050. lymphoma regression: a phase I/II study. J Clin Oncol 28:4324–4332,
198. Bridgeman A, et al: Viruses transfer the antiviral second messenger 2010. doi: 10.1200/JCO.2010.28.9793.
cGAMP between cells. Science 349:1228–1232, 2015. doi: 10.1126/ 220. Salazar AM, Erlich RB, Mark A, et al: Therapeutic in situ autovaccina-
science.aab3632. tion against solid cancers with intratumoral poly-ICLC: case report,
199. Silvin A, Manel N: Innate immune sensing of HIV infection. Curr Opin hypothesis, and clinical trial. Cancer Immunol Res 2:720–724, 2014.
Immunol 32:54–60, 2015. doi: 10.1016/j.coi.2014.12.003. doi: 10.1158/2326-6066.CIR-14-0024.
200. Herbeuval JP, et al: Regulation of TNF-related apoptosis-inducing 221. Andtbacka RH, et al: Talimogene laherparepvec improves durable
+
ligand on primary CD4 T cells by HIV-1: role of type I IFN-producing response rate in patients with advanced melanoma. J Clin Oncol
plasmacytoid dendritic cells. Proc Natl Acad Sci USA 102:13974–13979, 33:2780–2788, 2015. doi: 10.1200/JCO.2014.58.3377.
2005. doi: 10.1073/pnas.0505251102. 222. Kroemer G, Senovilla L, Galluzzi L, et al: Natural and therapy-induced
201. Herbeuval JP, et al: Differential expression of IFN-α and TRAIL/DR5 immunosurveillance in breast cancer. Nat Med 21:1128–1138, 2015.
in lymphoid tissue of progressor versus nonprogressor HIV-1-infected doi: 10.1038/nm.3944.

