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212 Part IV: Molecular and Cellular Hematology

58. Deveraux QL, Reed JC: IAP family proteins: Suppressors of apoptosis. Genes Dev 76. Miyashita T, Reed JC: Tumor suppressor p53 is a direct transcriptional activator of
13:239–252, 1999. human Bax gene. Cell 80:293–299, 1995.
59. Salvesen GS, Duckett CS: IAP proteins: Blocking the road to death’s door. Nat Rev Mol 77. Imamura J, Miyoshi I, Koeffler HP: p53 in hematologic malignancies. Blood 84(8):
Cell Biol 3:401–410, 2002. 2412–2421, 1994.
60. Giampietri C, Starace D, Petrungaro S, et al: Necroptosis: Molecular signalling and 78. Remstein ED, James CD, Kurtin PJ: Incidence and subtype specificity of API2-MALT1
translational implications. Int J Cell Biol 2014:490275, 2014. fusion translocations in extranodal, nodal, and splenic marginal zone lymphomas. Am
61. McComb S, Cheung HH, Korneluk RG, et al: cIAP1 and cIAP2 limit macrophage necrop- J Pathol 156(4):1183–1188, 2000.
tosis by inhibiting Rip1 and Rip3 activation. Cell Death Differ 19(11):1791–1801, 2012. 79. Shin MS, Kim HS, Kang CS, et al: Inactivating mutations of CASP10 gene in non
62. Karin M, Lin A: NF-kappaB at the crossroads of life and death. Nat Immunol 3:221–227, -Hodgkin lymphomas. Blood 99(11):4094–4099, 2002.
2002. 80. Gronbaek K, Straten PT, Ralfkiaer E, et al: Somatic Fas mutations in non-Hodgkin’s
63. Rane SG, Reddy EP: Janus kinases: Components of multiple signaling pathways. Onco- lymphoma: Association with extranodal disease and autoimmunity. Blood 92:
gene 19(49):5662–5679, 2000. 3018–3024, 1998.
64. Ahmed NN, Franke TF, Bellacosa A, et al: The proteins encoded by c-akt and v-akt dif- 81. Wu GS, Burns TF, McDonald ER 3rd, et al: KILLER/DR5 is a DNA damage-inducible
fer in post-translational modification, subcellular localization and oncogenic potential. p53-regulated death receptor gene. Nat Genet 17:141–143, 1997.
Oncogene 8:1957–1963, 1993. 82. Owen-Schaub LB, Zhang W, Cusack JC, et al: Wild-type human p53 and a temperature-
65. Datta S, Brunet A, Greenberg M: Cellular survival: A play in three Akts. Genes Dev sensitive mutant induce Fas/APO-1 expression. Mol Cell Biol 15(6):3032–3040, 1995.
13:2905–2927, 1999. 83. Momand J, Jung D, Wilczynski S, Niland J: The MDM2 gene amplification database.
66. Cardone MH, Roy N, Stennicke HR, et al: Regulation of cell death protease caspase-9 Nucleic Acids Res 26(15):3453–3459, 1998.
by phosphorylation. Science 282:1318–1320, 1998. 84. Drappa J, Vaishnaw AK, Sullivan KE, et al: Fas gene mutations in the Canale-Smith
67. Brunet A, Bonni A, Zigmond MJ, et al: Akt promotes cell survival by phosphorylating syndrome, an inherited lymphoproliferative disorder associated with autoimmunity. N
and inhibiting a forkhead transcription factor. Cell 96:857–868, 1999. Engl J Med 335(22):1643–1649, 1996.
68. Houldsworth J, Mathew S, Rao PH, et al: REL proto-oncogene is frequently amplified in 85. Watanabe-Fukunaga R, Brannan CI, Copeland NG, et al: Lymphoproliferation disor-
extranodal diffuse large cell lymphoma. Blood 87:25–29, 1996. der in mice explained by defects in Fas antigen that mediates apoptosis. Nature 356:
69. Karnolsky IN: Cytogenetic abnormalities in chronic lymphocytic leukemia. Folia Med- 314–317, 1992.
ica (Plovdiv) 42:5–10, 2000. 86. Takahashi T, Tanaka M, Brannan CI, et al: Generalized lymphoproliferative disease in
70. Karin M, Cao Y, Greten FR, Li Z-W: NF-kB in cancer: From innocent bystander to mice, caused by a point mutation in the Fas ligand. Cell 76:969–976, 1994.
major culprit. Nat Rev Cancer 2:301–310, 2002. 87. Fisher GH, Rosenberg FJ, Straus SE, et al: Dominant interfering fas gene mutations
71. Hayashi T, Faustman D: Essential role of human leukocyte antigen-encoded protea- impair apoptosis in a human autoimmune lymphoproliferative syndrome. Cell 81:
some subunits in NF-kappaB activation and prevention of tumor necrosis factor- alpha- 935–946, 1995.
induced apoptosis. J Biol Chem 275:5238–5247, 2000. 88. Wang J, Zheng L, Lobito A, et al: Inherited human Caspase 10 mutations underlie
72. Oda E, Ohki R, Murasawa H, et al: Noxa, a BH3-only member of the Bcl-2 family and defective lymphocyte and dendritic cell apoptosis in autoimmune lymphoproliferative
candidate mediator of p53-induced apoptosis. Science 288:1053–1058, 2000. syndrome type II. Cell 98(1):47–58, 1999.
73. Nakano K, Vousden KH: PUMA, a novel proapoptotic gene, is induced by p53. Mol Cell 89. Cantley L, Neel BG: New insights into tumor suppression: PTEN suppresses tumor
7:683–694, 2001. formation by restraining the phosphoinositide 3-kinase/AKT pathway. Proc Natl Acad
74. Yu J, Zhang L, Hwang PM, et al: PUMA induces the rapid apoptosis of colorectal cancer Sci U S A 96:4240–4245, 1999.
cells. Mol Cell 7:673–682, 2001. 90. Testa JR, Bellacosa A: AKT plays a central role in tumorigenesis. Proc Natl Acad Sci U S
75. Chipuk JE, Kuwana T, Bouchier-Hayes L, et al: Direct activation of Bax by p53 medi- A 98:10983–10985, 2001.
ates mitochondrial membrane permeabilization and apoptosis. Science 303:1010–1014,
2004.

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