Page 2373 - Williams Hematology ( PDFDrive )

2344 Part XIII: Transfusion Medicine Chapter 136: Erythrocyte Antigens and Antibodies 2345

(continued )

K: very common immune antibody Autoantibodies reported Fy a : common immune antibody Jk a : associated with delayed HTR; hemolytic; disappears quickly from serum Mild RBC destruction Lu glycoprotein on placental tissue may adsorb maternal Lu antibodies Xg a : poor immunogen Yt: some antibody examples clinically signifi- cant, others not Ch/Rg: associated with C4 complement, clini- cally insignificant antibodies Di a : antigen found in South American Indians and Asians Do a Do b : poor immunogens

2 — — 100 20 99 10 23 92 41 — — – – – – – – – – >99.9 – – – –

99.9 >99.9 >99.9 99.9 64(m) 89(f) 99.7 99.9 >99.9 Rare 100
9 2.3 — 66 83 77 72 7.7 8 96 98 10 67 83

Mild–Sev Mild–Sev Mild–Sev Mild–Mod Mild–Sev Mild–Sev Mild–Sev Mild Mild–Mod No–Mild No–Mild Mild No No No No No Mild–Sev Mild No Mild–Sev Mild +DAT +DAT

Yes Yes Yes Yes Yes Yes Yes Yes Yes Yes No Yes No No– Mod No No No No– Mod No– Mod No– Mild Yes No– Mod Yes Yes

Rare No No No No No Rare Rare Yes Yes No No Some No No No No Some Rare No Rare No No No

nc/D nc/D nc/D nc/D nc/D nc/D D/nc D/nc I/nc I/nc nc(V)/D nc(V)/D D/nc D(V)/D(V) D(V)/D D/nc D/nc nc/nc nc/nc nc/V nc/nc nc/nc nc/D(V) nc/D(V)

Most Most Most Most Rare — Most Most Most Most Few Most Most Most Most Most Most Most Most Most Most Most Most Most

Few Rare Rare Rare Rare — Rare Rare Rare Rare Most Few Rare No No – – Some Some – Some No No No

Most Most Most Most Most Most Most Most Most Most Few Some Most Most Most Most Most Most Most Most Most Most Most Most

Some — — — — — — — Few Few Some Some Some – – Rare – – – – – – –

General

Kp a Kp b Js b Fy a Fy b Jk a Jk b Lu a Lu b Xg a Yt a Yt b Ch Rg Co a Co b group Di a Di b Do a Do b
K k Js a

Kell Duffy Kidd Lutheran Xg Yt Ch/Rg Colton Cromer Diego Dom- brock

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