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2488 Index Index 2489
for follicular lymphoma, 1644, 1645–1647, Romiplostim Salt bridges, in deoxyhemoglobin, 761, 761f
1645t, 1646f, 1646t, 1649 adverse effects, 2006 SAMHD1, 231t
for γ-heavy-chain disease, 1806 for hypersplenism, 867 Sanger sequencing, 155
for gastric MALT lymphoma, 1666, 1666t for immune thrombocytopenia, 2001, 2006 SAO (Southeast Asian ovalocytosis), 670f,
for graft-versus-host disease prophylaxis, for myelodysplastic syndromes, 1358, 2384 680
372 RORγt (retinoic acid-related orphan receptor SAP (SLAM-associated protein), 1228
for Hodgkin lymphoma, 1616, 1617 γ), 1181f, 1182 Saposin C, 1122
for immune thrombocytopenia, 122, 2000, ROS (reactive oxygen species), 195–196, 1663 SARA (SMAD anchor for receptor
2005 Rosai-Dorfman disease (sinus histiocytosis activation), 251
for intravascular large B-cell lymphoma, with massive lymphadenopathy), Sarcoidosis, 1097, 1575
1636 1101, 1112–1113 Sarcoma
for mantle cell lymphoma, 1655–1656, Rosette test, 859 dendritic cell, 1110
1656f, 1657t, 1658, 1658t, 1659t, Rotational thromboelastography, 2206–2207 extranodal histiocytic, 1110
1660t Rouleaux, 21 Langerhans cell, 1110
for μ-heavy-chain disease, 1810 RPS14, 539, 1347 lympho-, 1569, 1603
for posttransplantation RPS19, 539, 540 mast cell, 978
lymphoproliferative disease, 1266, rPTKs (receptor protein-tyrosine kinases), myeloid, 1381
1636 230 nonleukemic myeloid, 1398
in pregnancy, 1634 rRNA (ribosomal RNA), 147, 195 reticulum cell, 1569
for primary cutaneous diffuse large B-cell RSS (recombination signal sequences), 1164 Sarcoplasmic reticulum, 1836
lymphoma, leg type, 1637 RSV (respiratory syncytial virus) infection, Sarcosine dehydrogenase, 588
for primary mediastinal large B-cell 384, 386 Sargramostim, 1358. See also Granulocyte-
lymphoma, 1634 RTKs (receptor tyrosine kinases), 249 macrophage colony-stimulating
for pure red cell aplasia, 544 Rubella, mononucleosis and, 1268 factor (GM-CSF)
in reduced-intensity conditioning, 360 Rubor, 508 SARM (sterile-α and armadillo motif), 298
resistance to, 344 RUNX1, 1817 Saruplase, 2313t
for splenic marginal zone lymphoma, 1667 RUNX1 (AML1) Satellitism, platelet-leukocyte, 1995, 1995f
for thrombocytopenia, 2008 in acute myelogenous leukemia, 181t, 225, Satiety, premature, history of, 5
for thrombotic thrombocytopenic 226t, 237, 1376, 1378, 1378t, 1384t, SBDS, 532
purpura, 2256 1415, 2060 Sca1, 260
for Waldenström macroglobulinemia, 1794 in congenital neutropenia, 993 Scar tissue, 280
Rivaroxaban, 401–402 in myelodysplastic syndromes, 181t, 228t, Scavenger receptor-B1 (SCARB1, CLA-1),
adverse effects, 2275t 1345, 1346t, 1351 1872
for antiphospholipid syndrome, 2245 RUNX1-RUNX1T1 rearrangement, 225 Scavenger receptor-B3 (SCARB3). See
clinical studies, 400t RUNXT1 (ETO), 1351, 1384t, 1414 Glycoprotein (GP)IV
mechanism of action, 1922 Russell bodies, 1742, 1743f Scavenger receptors (SRs), 1054–1055, 1057t,
for venous thromboembolism, 2274–2275, Ruxolitinib, 341–342 1872, 2287
2274t, 2275t for polycythemia vera, 1300 SCF. See Stem cell factor (SCF)
RLH (RIG-I-like helicase) pathway, 300–303 for primary myelofibrosis, 1329, 1329t Schilling test, 584
R-MCP regimen Schimke syndrome, 1226
for follicular lymphoma, 1646t S Schistosoma, 956, 957t, 1180
for mantle cell lymphoma, 1657t S1P (sphingosphine-1-phosphate), 1857, Schistosomula, killing of, 953
RMRP, 1226 1878 Schizocytes (schistocytes), 21f, 472f, 472t,
RNA, 147, 153. See also mRNA (messenger S100A9 (MRP-14), 1856, 1872 475, 2255–2256
RNA) S100A10, 2309 Schnitzler syndrome, 1791
RNA-induced silencing complex (RISC), 153 S-adenosylhomocysteine (SAH), 588 Scianna blood group/antigens, 2331t, 2337,
RNA polymerase, 147 S-adenosylmethionine (SAMe), 196, 590 2346t
RNA sequencing, 161, 1851, 1852f SAGE (serial analysis of gene expression), SCID. See Severe combined
ROBO1, 1737 421 immunodeficiency (SCID)
Rocky Mountain spotted fever, 2105, 2105f SAH (S-adenosylhomocysteine), 588 SCL (stem cell leukemia), 262
Rofecoxib, 2075 SAHA (suberoylanilide hydroxamic acid), SCL40A1, 642
Romidepsin, 336–337 1403 SCL/TAL1 (stem cell leukemia/T-cell acute
for acute myelogenous leukemia, 1403 Salicylates, 112 lymphoblastic leukemia 1), 484
for mycosis fungoides, 1687 Saline (direct) agglutinins, 823 SCNT (somatic cell nuclear transfer), 448
for peripheral T-cell lymphoma, 1696, Salmonella spp., 819 Scorpion bites, 809
1696t Salmonella typhimurium, 1066f Scott syndrome, 2058–2059
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