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 2488  Index                                                                                            Index         2489



                    for follicular lymphoma, 1644, 1645–1647,   Romiplostim                Salt bridges, in deoxyhemoglobin, 761, 761f
                         1645t, 1646f, 1646t, 1649      adverse effects, 2006              SAMHD1, 231t
                    for γ-heavy-chain disease, 1806     for hypersplenism, 867             Sanger sequencing, 155
                    for gastric MALT lymphoma, 1666, 1666t  for immune thrombocytopenia, 2001, 2006  SAO (Southeast Asian ovalocytosis), 670f,
                    for graft-versus-host disease prophylaxis,   for myelodysplastic syndromes, 1358, 2384  680
                         372                          RORγt (retinoic acid-related orphan receptor   SAP (SLAM-associated protein), 1228
                    for Hodgkin lymphoma, 1616, 1617         γ), 1181f, 1182               Saposin C, 1122
                    for immune thrombocytopenia, 122, 2000,   ROS (reactive oxygen species), 195–196, 1663  SARA (SMAD anchor for receptor
                         2005                         Rosai-Dorfman disease (sinus histiocytosis   activation), 251
                    for intravascular large B-cell lymphoma,   with massive lymphadenopathy),   Sarcoidosis, 1097, 1575
                         1636                                1101, 1112–1113               Sarcoma
                    for mantle cell lymphoma, 1655–1656,   Rosette test, 859                dendritic cell, 1110
                         1656f, 1657t, 1658, 1658t, 1659t,   Rotational thromboelastography, 2206–2207  extranodal histiocytic, 1110
                         1660t                        Rouleaux, 21                          Langerhans cell, 1110
                    for μ-heavy-chain disease, 1810   RPS14, 539, 1347                      lympho-, 1569, 1603
                    for posttransplantation           RPS19, 539, 540                       mast cell, 978
                         lymphoproliferative disease, 1266,   rPTKs (receptor protein-tyrosine kinases),   myeloid, 1381
                         1636                                230                            nonleukemic myeloid, 1398
                    in pregnancy, 1634                rRNA (ribosomal RNA), 147, 195        reticulum cell, 1569
                    for primary cutaneous diffuse large B-cell   RSS (recombination signal sequences), 1164  Sarcoplasmic reticulum, 1836
                         lymphoma, leg type, 1637     RSV (respiratory syncytial virus) infection,   Sarcosine dehydrogenase, 588
                    for primary mediastinal large B-cell     384, 386                      Sargramostim, 1358. See also Granulocyte-
                         lymphoma, 1634               RTKs (receptor tyrosine kinases), 249       macrophage colony-stimulating
                    for pure red cell aplasia, 544    Rubella, mononucleosis and, 1268            factor (GM-CSF)
                    in reduced-intensity conditioning, 360  Rubor, 508                     SARM (sterile-α and armadillo motif), 298
                    resistance to, 344                RUNX1, 1817                          Saruplase, 2313t
                    for splenic marginal zone lymphoma, 1667  RUNX1 (AML1)                 Satellitism, platelet-leukocyte, 1995, 1995f
                    for thrombocytopenia, 2008          in acute myelogenous leukemia, 181t, 225,   Satiety, premature, history of, 5
                    for thrombotic thrombocytopenic          226t, 237, 1376, 1378, 1378t, 1384t,   SBDS, 532
                         purpura, 2256                       1415, 2060                    Sca1, 260
                    for Waldenström macroglobulinemia, 1794  in congenital neutropenia, 993  Scar tissue, 280
                  Rivaroxaban, 401–402                  in myelodysplastic syndromes, 181t, 228t,   Scavenger receptor-B1 (SCARB1, CLA-1),
                    adverse effects, 2275t                   1345, 1346t, 1351                    1872
                    for antiphospholipid syndrome, 2245  RUNX1-RUNX1T1 rearrangement, 225  Scavenger receptor-B3 (SCARB3). See
                    clinical studies, 400t            RUNXT1 (ETO), 1351, 1384t, 1414             Glycoprotein (GP)IV
                    mechanism of action, 1922         Russell bodies, 1742, 1743f          Scavenger receptors (SRs), 1054–1055, 1057t,
                    for venous thromboembolism, 2274–2275,   Ruxolitinib, 341–342                 1872, 2287
                         2274t, 2275t                   for polycythemia vera, 1300        SCF. See Stem cell factor (SCF)
                  RLH (RIG-I-like helicase) pathway, 300–303  for primary myelofibrosis, 1329, 1329t  Schilling test, 584
                  R-MCP regimen                                                            Schimke syndrome, 1226
                    for follicular lymphoma, 1646t    S                                    Schistosoma, 956, 957t, 1180
                    for mantle cell lymphoma, 1657t   S1P (sphingosphine-1-phosphate), 1857,   Schistosomula, killing of, 953
                  RMRP, 1226                                 1878                          Schizocytes (schistocytes), 21f, 472f, 472t,
                  RNA, 147, 153. See also mRNA (messenger   S100A9 (MRP-14), 1856, 1872           475, 2255–2256
                         RNA)                         S100A10, 2309                        Schnitzler syndrome, 1791
                  RNA-induced silencing complex (RISC), 153  S-adenosylhomocysteine (SAH), 588  Scianna blood group/antigens, 2331t, 2337,
                  RNA polymerase, 147                 S-adenosylmethionine (SAMe), 196, 590       2346t
                  RNA sequencing, 161, 1851, 1852f    SAGE (serial analysis of gene expression),   SCID. See Severe combined
                  ROBO1, 1737                                421                                  immunodeficiency (SCID)
                  Rocky Mountain spotted fever, 2105, 2105f  SAH (S-adenosylhomocysteine), 588  SCL (stem cell leukemia), 262
                  Rofecoxib, 2075                     SAHA (suberoylanilide hydroxamic acid),   SCL40A1, 642
                  Romidepsin, 336–337                        1403                          SCL/TAL1 (stem cell leukemia/T-cell acute
                    for acute myelogenous leukemia, 1403  Salicylates, 112                        lymphoblastic leukemia 1), 484
                    for mycosis fungoides, 1687       Saline (direct) agglutinins, 823     SCNT (somatic cell nuclear transfer), 448
                    for peripheral T-cell lymphoma, 1696,   Salmonella spp., 819           Scorpion bites, 809
                         1696t                        Salmonella typhimurium, 1066f        Scott syndrome, 2058–2059








          Kaushansky_index_p2393-2506.indd   2489                                                                       9/21/15   3:22 PM
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