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 2492  Index                                                                                            Index         2493



                  Spooning, purpura and, 2107         STEAP3, 623                           X-linked agammaglobulinemia and, 1212
                  Spur cell. See Acanthocytes         STEC-HUS (Shiga toxin E. coli-associated   Streptokinase, 402–403
                  Spur cell anemia. See Acanthocytosis       hemolytic uremic syndrome), 2255,   for acute myocardial infarction, 2295
                  Spur cell hemolytic anemia, 655            2258–2259                      clinical uses, 403
                  SR-A I/II, 1055, 1057t              Steel factor. See Stem cell factor (SCF)  comparison to other fibrinolytic agents,
                  Src, 1884                           Stem cell factor (SCF)                      2313t
                  SRs (scavenger receptors), 1054–1055, 1057t,   aplastic anemia and, 519   mechanism of action, 402–403
                         1872                           components, 218                     for peripheral vascular disease, 2316
                  SRSF2, 227t, 1346t, 1349, 1468, 1468t  in hematopoiesis, 253, 264–265, 264t, 266  platelet function and, 2078
                  SRT (substrate reduction therapy), 1128, 1130  mast cells and, 966        for stroke, 2315
                  SS (Sézary syndrome), 1498t, 1679, 1683t,   in megakaryopoiesis, 1817, 1821  Streptomyces pilosus, 644
                         1684t. See also Cutaneous T-cell   synthesis, 265                 Streptomyces verticillus, 331
                         lymphoma (CTCL)              Stem cell leukemia (SCL), 262        Stress lymphocytosis, 1204
                  STAG2, 1346t, 1352                  Stem cell leukemia/T-cell acute lymphoblastic   Stress polycythemia, 872
                  Stanford CVP regimen, for follicular       leukemia 1 (SCL/TAL1), 484    Stress reticulocytes, 467, 482f, 505
                         lymphoma, 1645t              Stem cells. See Hematopoietic stem cells   Stroke
                  Stanford V regimen, for Hodgkin lymphoma,   (HSCs); Multipotential cells  antiphospholipid syndrome and,
                         1612t, 1614, 1615t           Stem cell transplantation. See Hematopoietic   2238–2239
                  Staphylococcus aureus                      cell transplantation (HCT)     double platelet blockade and, 2076
                    methicillin-resistant, 384–385    STEMI (ST-segment elevation myocardial   etiology and pathogenesis, 2297
                    vancomycin-resistant, 385                infarction). See Myocardial    fibrinolytic therapy for, 2313–2316
                  Staphylococcus infections                  infarction (MI)                  clinical studies, 2314, 2314t
                    in Chédiak-Higashi syndrome, 1018  Sterile inflammation (autoinflammatory   intraarterial thrombolysis, 2315–2316
                    in chronic granulomatous disease, 1030,   disease), 298                   patient selection, 2313t
                         1032                         Sterile-α and armadillo motif (SARM), 298  principles, 2314–2315
                    disseminated intravascular coagulation   Sternum, history of tenderness of, 5  streptokinase, 2315
                         and, 2207                    Steroids. See Glucocorticoids           tenecteplase, 2315
                    in hyperimmunoglobulin E syndrome, 985  Stevens-Johnson syndrome, 2075, 2106  tissue-type plasminogen activator,
                    in leukocyte adhesion deficiency, 1023  Stibophen, drug-related hemolytic anemia   2314–2315, 2316t
                    neutropenia and, 522, 985                and, 824                       integrin α β  blockers for, 1855
                                                                                                   IIb 3
                    neutrophil abnormalities and, 986  Stiff heart syndrome, 1777           in sickle cell disease, 769–770
                    in neutrophil motility disorders, 1026  STIM1 (stromal interaction molecule 1),   therapy, 2297
                    in newborn, 106                          1221, 1836                    Stroma, histogenesis of, 55
                    in specific granule deficiency, 1021  STING (stimulator of IFN genes), 302, 302f  Stromal cell-derived factor-1. See CXCL12
                    Th17 T cells and, 1182            Stoddard solvent, 517                       (stromal cell-derived factor-1)
                    in X-linked agammaglobulinemia, 1030  Stomach, primary lymphoma in, 1581  Stromal cells, 264
                  Staphylokinase, 2313t, 2316         Stomatin, 663t                       Stromal interaction molecule 1 (STIM1),
                  Starvation, anemia of, 654          Stomatocytes, 21f, 472f, 472t, 473, 474f, 671f  1221, 1836
                  STAT, 252                           Stomatocytic elliptocytosis. See Southeast   Stromal microenvironment, aplastic anemia
                  STAT1 deficiency, 1231                     Asian ovalocytosis (SAO)             and, 519
                  STAT1 gain-of-function mutations, 1223,   Stomatocytosis                 Stromatin, 1013
                         1231                           acquired, 684                      Strongyloides, 956, 957t
                  STAT3, 1026, 1181f, 1182, 1379, 1528  hereditary. See Hereditary stomatocytosis   Strongyloidiasis, 1203, 2105, 2105f
                  STAT3, 237t, 1215t, 1223–1224, 1225, 1564  syndromes                     STRs (short tandem repeats), 147
                  STAT4, 1643                         Storage pool disease, 2085           ST-segment elevation myocardial infarction
                  STAT5, 485, 486f, 1180, 1181f, 1444, 1606  Streptococcus infections             (STEMI). See Myocardial infarction
                  STAT5b deficiency, 1223               chronic inflammation and, 290             (MI)
                  STAT6, 1180                           cytarabine therapy and, 322        Stuart-Prower factor. See Factor X
                  STAT6, 236t                           disseminated intravascular coagulation   Stuttering priapism, 770
                  Statins                                    and, 2207                     STXB5/STXB5, 1849, 2061
                    for acute myelogenous leukemia, 1403  hyposplenism and, 868            Subacute leukemia. See Oligoblastic
                    for antiphospholipid syndrome, 2245  in immunocompromised host, 383           myelogenous leukemia (refractory
                    CD40 expression and, 2288           red cell antigens and susceptibility to, 2340  anemia with excess blasts)
                    for myocardial infarction, 2296     thrombotic microangiopathy and,    Subcutaneous fat aspiration, 1776, 1776f
                  STAT proteins, 932                         2261–2262                     Subcutaneous panniculitis-like T-cell
                  Stavudine, 1249, 1252                 vaccination, 869                          lymphoma, 1498t, 1702








          Kaushansky_index_p2393-2506.indd   2493                                                                       9/21/15   3:22 PM
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