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2492 Index Index 2493
Spooning, purpura and, 2107 STEAP3, 623 X-linked agammaglobulinemia and, 1212
Spur cell. See Acanthocytes STEC-HUS (Shiga toxin E. coli-associated Streptokinase, 402–403
Spur cell anemia. See Acanthocytosis hemolytic uremic syndrome), 2255, for acute myocardial infarction, 2295
Spur cell hemolytic anemia, 655 2258–2259 clinical uses, 403
SR-A I/II, 1055, 1057t Steel factor. See Stem cell factor (SCF) comparison to other fibrinolytic agents,
Src, 1884 Stem cell factor (SCF) 2313t
SRs (scavenger receptors), 1054–1055, 1057t, aplastic anemia and, 519 mechanism of action, 402–403
1872 components, 218 for peripheral vascular disease, 2316
SRSF2, 227t, 1346t, 1349, 1468, 1468t in hematopoiesis, 253, 264–265, 264t, 266 platelet function and, 2078
SRT (substrate reduction therapy), 1128, 1130 mast cells and, 966 for stroke, 2315
SS (Sézary syndrome), 1498t, 1679, 1683t, in megakaryopoiesis, 1817, 1821 Streptomyces pilosus, 644
1684t. See also Cutaneous T-cell synthesis, 265 Streptomyces verticillus, 331
lymphoma (CTCL) Stem cell leukemia (SCL), 262 Stress lymphocytosis, 1204
STAG2, 1346t, 1352 Stem cell leukemia/T-cell acute lymphoblastic Stress polycythemia, 872
Stanford CVP regimen, for follicular leukemia 1 (SCL/TAL1), 484 Stress reticulocytes, 467, 482f, 505
lymphoma, 1645t Stem cells. See Hematopoietic stem cells Stroke
Stanford V regimen, for Hodgkin lymphoma, (HSCs); Multipotential cells antiphospholipid syndrome and,
1612t, 1614, 1615t Stem cell transplantation. See Hematopoietic 2238–2239
Staphylococcus aureus cell transplantation (HCT) double platelet blockade and, 2076
methicillin-resistant, 384–385 STEMI (ST-segment elevation myocardial etiology and pathogenesis, 2297
vancomycin-resistant, 385 infarction). See Myocardial fibrinolytic therapy for, 2313–2316
Staphylococcus infections infarction (MI) clinical studies, 2314, 2314t
in Chédiak-Higashi syndrome, 1018 Sterile inflammation (autoinflammatory intraarterial thrombolysis, 2315–2316
in chronic granulomatous disease, 1030, disease), 298 patient selection, 2313t
1032 Sterile-α and armadillo motif (SARM), 298 principles, 2314–2315
disseminated intravascular coagulation Sternum, history of tenderness of, 5 streptokinase, 2315
and, 2207 Steroids. See Glucocorticoids tenecteplase, 2315
in hyperimmunoglobulin E syndrome, 985 Stevens-Johnson syndrome, 2075, 2106 tissue-type plasminogen activator,
in leukocyte adhesion deficiency, 1023 Stibophen, drug-related hemolytic anemia 2314–2315, 2316t
neutropenia and, 522, 985 and, 824 integrin α β blockers for, 1855
IIb 3
neutrophil abnormalities and, 986 Stiff heart syndrome, 1777 in sickle cell disease, 769–770
in neutrophil motility disorders, 1026 STIM1 (stromal interaction molecule 1), therapy, 2297
in newborn, 106 1221, 1836 Stroma, histogenesis of, 55
in specific granule deficiency, 1021 STING (stimulator of IFN genes), 302, 302f Stromal cell-derived factor-1. See CXCL12
Th17 T cells and, 1182 Stoddard solvent, 517 (stromal cell-derived factor-1)
in X-linked agammaglobulinemia, 1030 Stomach, primary lymphoma in, 1581 Stromal cells, 264
Staphylokinase, 2313t, 2316 Stomatin, 663t Stromal interaction molecule 1 (STIM1),
Starvation, anemia of, 654 Stomatocytes, 21f, 472f, 472t, 473, 474f, 671f 1221, 1836
STAT, 252 Stomatocytic elliptocytosis. See Southeast Stromal microenvironment, aplastic anemia
STAT1 deficiency, 1231 Asian ovalocytosis (SAO) and, 519
STAT1 gain-of-function mutations, 1223, Stomatocytosis Stromatin, 1013
1231 acquired, 684 Strongyloides, 956, 957t
STAT3, 1026, 1181f, 1182, 1379, 1528 hereditary. See Hereditary stomatocytosis Strongyloidiasis, 1203, 2105, 2105f
STAT3, 237t, 1215t, 1223–1224, 1225, 1564 syndromes STRs (short tandem repeats), 147
STAT4, 1643 Storage pool disease, 2085 ST-segment elevation myocardial infarction
STAT5, 485, 486f, 1180, 1181f, 1444, 1606 Streptococcus infections (STEMI). See Myocardial infarction
STAT5b deficiency, 1223 chronic inflammation and, 290 (MI)
STAT6, 1180 cytarabine therapy and, 322 Stuart-Prower factor. See Factor X
STAT6, 236t disseminated intravascular coagulation Stuttering priapism, 770
Statins and, 2207 STXB5/STXB5, 1849, 2061
for acute myelogenous leukemia, 1403 hyposplenism and, 868 Subacute leukemia. See Oligoblastic
for antiphospholipid syndrome, 2245 in immunocompromised host, 383 myelogenous leukemia (refractory
CD40 expression and, 2288 red cell antigens and susceptibility to, 2340 anemia with excess blasts)
for myocardial infarction, 2296 thrombotic microangiopathy and, Subcutaneous fat aspiration, 1776, 1776f
STAT proteins, 932 2261–2262 Subcutaneous panniculitis-like T-cell
Stavudine, 1249, 1252 vaccination, 869 lymphoma, 1498t, 1702
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