Page 136 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPTEr 7 B-Cell Development and Differentiation 118.e1

MULTIPLE-CHOICE QUESTIONS

1. The first quality control checkpoint for immunoglobulin H 3. The best cell surface marker for B cells is:
chain function occurs at what stage of B-cell development? A. CD10
A. ProB cells B. CD19
B. PreB cells C. CD20
C. Immature B cells D. CD21
D. Transitional B cells E. CD24
E. B-1 cells
4. Which one of the following is a transcription factor critical
2. Somatic hypermutation (SHM) occurs at what stage of B-cell for B-cell development?
development? A. TdT
A. ProB cells B. PAX5
B. PreB cells C. LCK
C. B-1 cells D. BLNK
D. Marginal zone (MZ) B cells E. BTK
E. Germinal center (GC) B cells