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CHaPtEr 15  Immunoglobulin Function             233.e1


              MUL t IPLE-CH o ICE QUES t I o NS

           1.  For which of the following phenomena is intrinsic affinity   3.  Which of the following Fcγ receptors transduces signals that
             necessarily more important than functional affinity?   inhibit activation of B lymphocytes?
              A. Antibody-mediated opsonization of encapsulated bacterial    A. FcεRI
               pathogens                                             B. FcεRII
              B. Assay using antibodies to detect small drugs in solution   C. FcγR1
              C. Binding of C1q to immunoglobulin G (IgG) or IgM     D. FcγRIIA
              D. Binding of neutralizing IgG antibodies to nonenveloped    E.  FcγRIIB1
               viruses
                                                                  4.  Which of the following immunoglobulin (Ig) isotypes is
           2.  Which of the following human immunoglobulin G (IgG)   dominant in colostrum and intestinal secretions?
             subclasses is the least effective in activating the classical pathway    A. IgA1
             of complement?                                          B. IgG2
              A. IgG1                                                C. IgG3
              B. IgG2                                                D. IgD
              C. IgG3                                                E.  IgE
              D. IgG4
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