Page 529 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPTEr 35 Primary T-Cell Immunodeficiencies 508.e1

M u LTIPLE-CHOICE Q u ESTIONS

1. Each of these comments about T-cell deficiencies (severe B. In vitro responses to mitogens can be normal in some
combined immunodeficiency/combined immunodeficiency cases.
[SCID/CID]) are TRUE, except: C. Evaluation of natural killer (NK) cell numbers and function
A. Patients may present in infancy with failure to thrive. can be beneficial for diagnosis.
B. The thymus always appears dysplastic. D. Serum immunoglobulin levels can be normal.
C. Malignancy could be the sole presenting feature. E. CH50 does not contribute to the diagnosis.
D. Clinical manifestations may first arise during late childhood 3. For which of the following conditions is hematopoietic stem
or adolescence. cell transplantation not recommended?
E. Patients may present with severe hypocalcaemia.
A. FOXP3 deficiency
2. Which of the following is INCORRECT? B. Ataxia telangiectasia
A. All patients who present with a SCID phenotype can be C. Major histocompatibility complex (MHC) class II deficiency
detected at birth by T-cell receptor excision circle (TREC) D. Adenosine deaminase (ADA) deficiency
analysis E. DOCK2 deficiency