Page 872 - Clinical Immunology_ Principles and Practice ( PDFDrive )

CHaPTEr 61 Antiphospholipid Syndrome 841.e1

MULT i PLE-CHO i CE QUEST i ONS

1. Which of the following statements concerning treatment 3. Which of the following patients should be tested for possible
options for a patient with antiphospholipid antibodies is APS?
correct? A. A 65 year old man with a stroke
A. Aspirin is an effective thromboprophylactic strategy B. A 22 year old woman taking oral contraceptives with a
for asymptomatic individuals with antiphospholipid pulmonary embolism
antibodies. C. A 34 year old woman who presents with fetal demise at
B. Patients with arterial thromboembolism and APS should 34 weeks gestation
be treated with aspirin and a direct oral anticoagulant D. A 27 year old man new-onset seizures
C. Patients with venous thromboembolism and APS should
be treated with warfarin with a target INR of 2-3
D. A woman with prior pregnancy loss and APS should receive
intravenous immunoglobulin and steroids during subse-
quent pregnancies
2. A lupus anticoagulant is identified by which of the following
laboratory test results?
A. Elevated antibody levels to prothrombin
B. An antibody that interferes with phospholipid-dependent
coagulation reactions
C. An antibody that induces an increased thrombin potential
D. The presence of a specific factor inhibitor