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CHAPTER 111: Preoperative Assessment of the High-Risk Surgical Patient  1053


                      3.  Adequate treatment of sepsis and shock, with recognition of the   CHAPTER  Preoperative Assessment
                       important role of surgery or interventional radiology in the iden-
                       tification and drainage of areas of sepsis such as intra-abdominal   of the High-Risk Surgical
                       abscesses.                                          111
                      4.  Judicious use of intravenous fluids to maintain adequate perfusion   Patient
                       while avoiding overhydration and pulmonary edema.              Robert Chen
                      5.  Optimal use of analgesics to control pain without producing    Jameel Ali
                       respiratory depression.
                      6.  Administration of supplemental oxygen to hypoxemic patients to
                       improve arterial oxygenation.                       KEY POINTS
                      7.  Treatment (as specific as possible) of any identifiable cause of     • Perioperative risk assessment by careful history, physical examina-
                       hypoxemia; for example, bronchodilator therapy for a patient with   tion, and selective investigation is essential for directing therapy in
                       bronchospasm, or antibiotic therapy directed against a specific   the high-risk surgical patient.
                       organism isolated in a patient with a pneumonic process.    • To decrease mortality and morbidity, major medical illnesses must
                      8.  Preoperative pulmonary assessment, especially in patients with   be identified and appropriately managed.
                       poor pulmonary reserve and most especially in those undergoing     • Delirium is a common postoperative complication that can be
                       lung resection. This will allow an assessment of the relative risk of   anticipated given risk factors.
                       postoperative morbidity.
                      9.  Institution of mechanical ventilation when the above measures fail.     • Perioperative cardiac morbidity can be minimized with  preemptive
                                                                            medical management which includes the perioperative administra-
                       Frequently, mechanical ventilation can be avoided if strict attention   tion of β-blockers in very select patients.
                       is paid to preventive measures. Also, vigorous application of these
                       principles immediately after the patient is stabilized can shorten the     • Postoperative pulmonary complications can be reduced by aggres-
                       duration of mechanical ventilation considerably. 76,77  sive pre- and postoperative care.
                                                                              • Diabetes mellitus and steroid dependence must be completely
                                                                            managed to significantly influence perioperative morbidity and
                                                                            mortality.
                     KEY REFERENCES

                        • Ali J, Weisel RD, Layug AB, et al. Consequences of postoperative
                       alterations in respiratory mechanics. Am J Surg. 1974;128:376.
                        • Burch JM, Ortiz VB, Richardson RJ, et al. Abbreviated laparotomy   As indicated in Chap.110, surgery and anesthesia trigger a host of physi-
                       and planned reoperation for critically injured patients. Ann Surg.   ologic responses. Anesthesiologists have described elective surgery as
                       1991;215:476.                                      “planned trauma.” Thus they prepare for all the traumatic sequelae that
                        • Casaer MP, Mesotten D, Hermans G, et al. Early versus late     will occur such as blood loss and fluid shifts, increased myocardial oxygen
                       parenteral nutrition in critically ill adults.  N  Engl  J  Med. 2011;   demands, respiratory changes caused by intubation and ventilation with
                       365:506.                                           supplemental oxygen, increased plasma cortisol of the stress response,
                        • Craig DB, Wahba WM, Don HF, et al. “Closing volume” and its   and  coagulopathy  to  name  a  few.  In  the  average  otherwise  healthy
                       relationship to gas exchange in seated and supine positions. J Appl   patient, these responses result in no major untoward postoperative
                       Physiol. 1971;31:717.                              events. However, in the medically compromised patient, the additional
                                                                          burden of surgical stress can prove to be very challenging and sometimes
                        • CRASH-2 Trial Collaborators. Effects of tranexamic acid on   insurmountable. Such patients frequently require detailed evaluation and
                       death, vascular occlusive events, and blood transfusion in trauma   monitoring in the preoperative as well as postoperative periods in the
                       patients with significant hemorrhage (CRASH-2): a randomised,   intensive care unit (ICU). Careful planning, preoperative assessment, and
                       placebo-controlled trial. Lancet. 2010;376:23.     management of identified abnormalities in these patients are crucial to
                        • Fouche Y, Sikorski R, Dutton RP. Changing paradigms in surgical   optimize chances of a good postoperative outcome. A major component
                       resuscitation. Crit Care Med. 2010;38(9):S411.     of this planning involves the assessment of risks for intraoperative and
                        • Griesdale DE, De Souza RJ, Van Dam RM, et al. Intensive   postoperative morbidity. Patients with cardiac, respiratory, and renal
                       insulin therapy and mortality among critically ill patients: a   abnormalities pose special risks for postoperative complications. In this
                       meta-analysis including NICE-SUGAR study data. CMAJ. 2009;   chapter, we present guidelines for identifying and managing patients at
                       180(8):827.                                        risk of developing postoperative morbidity.
                        • Magder S. Clinical usefulness of respiratory variations in arterial
                       pressure. Am J Respir Crit Care Med. 2004;169:151.  PREOPERATIVE SCREENING
                        • Moore FA, Feliciano DV, Andrassy RJ, et al. Early enteral feeding,   Table 111-1 is a system of perioperative screening for patients at
                       compared with parenteral, reduces postoperative septic complica-  St Michael’s Hospital in Toronto, Canada. Patients identified preop-
                       tions: the results of a meta-analysis. Ann Surg. 1992;216:172.  eratively with severe disease (Table 111-1) or gravid patients for non-
                        • von Ungern-Sternberg BS, Regli A, Schneider MC, et al. Effect   obstetric surgery should be seen by an anesthesiologist in an outpatient
                       of obesity and site of surgery on perioperative lung volumes. Br J   clinic where there is time for preoperative risk stratification and disease
                       Anaesth. 2004;92:202.                                optimization if possible. If conditions are found that warrant a delay in
                                                                          surgery, early identification minimizes the impact of other scheduled sur-
                                                                          geries. At that juncture, additional advice from Internal Medicine or medi-
                                                                          cal subspecialties is sought as necessary for postoperative management.
                    REFERENCES                                             Codifying or classification leads to more rapid and precise com-
                                                                          munication among clinicians: shock classification, solid organ injury
                    Complete references available online at www.mhprofessional.com/hall  grading, and subarachnoid hemorrhage classification are such examples.








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