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1060     PART 10: The Surgical Patient


                 therapy exceeding this amount is beneficial. Patients on chronic   CHAPTER  Principles of Postoperative
                 steroid therapy undergoing minor surgery should have their regular
                 steroid dose on the morning of surgery and no additional doses if sur-  Critical Care
                 gery is uncomplicated. Candidates for major surgery should receive no  112
                 more than physiologic doses of glucocorticoid. A regime might consist   Jonathan Simmons
                 of 25 mg hydrocortisone intravenously on induction of anesthesia, and   Laura A. Adam
                 100 to 150 mg per day over the following 24 to 72 hours. If a patient
                 presenting for surgery is already receiving a maintenance steroid dose
                 greater than the estimated requirement, additional steroid coverage is   KEY POINTS
                 not necessary. 90,91
                   Clinical and biochemical preoperative assessment of patients on     • The initial sign that a malignant hyperthermia crisis is developing is
                 chronic steroid therapy is invaluable in the identification of patients   a rise in end-tidal CO  levels. The treatment of choice is dantrolene.
                                                                                         2
                 at risk for adrenal insufficiency in the perioperative period. Published     • Twitch monitors should be utilized to ensure that neuromuscular
                 recommendations for supplemental steroid coverage should be followed   blockade has been adequately reversed as physical examination is
                 by dosing to physiologic levels.                         not generally adequate. Residual neuromuscular blockade is an
                                                                          important cause of postoperative respiratory failure.
                                                                           • Unfractionated heparin for DVT prophylaxis offers no benefit for
                                                                          trauma  patients.  Low-molecular-weight  heparin  should  be  used
                  KEY REFERENCES                                          unless contraindicated.
                     • Bonow RO, Carabello BA, Chatterjee K, et al. 2008 focused     • Patients with systolic anterior motion (SAM) of the mitral valve
                    update incorporated into the ACC/AHA 2006 guidelines for the   or significant ventricular hypertrophy should undergo fluid resus-
                    management of patients with valvular heart disease: a report of   citation as the mainstay of post-cardiac surgery management as
                    the American College of Cardiology/American Heart Association   inotropes may cause severe obstructive cardiogenic shock.
                    Task Force  on  Practice  Guidelines (Writing  Committee to     • Cardiac tamponade, massive hemothorax, and right heart  failure
                    revise the 1998 guidelines for the management of patients with     are significant causes of morbidity and mortality in cardiac
                    valvular heart disease).  J Am Coll Cardiol. September 23, 2008;   surgery. Their presentations can be similar and distinguishing
                    52(13):e1-e142.                                       between the different causes is imperative to ensure that proper
                     • Celli BR, Rodriguez KS, Snider GL. A controlled trial of intermit-  medical and/or surgical treatment is performed.
                    tent  positive pressure  breathing exercises  in  preventing  pulmo-    • Inhaled pulmonary vasodilators are important adjuncts in the
                    nary complications after abdominal surgery. Am Rev Respir Dis.   treatment of acute right heart failure in the postoperative period
                    1984;130:12.                                          as they do not have the systemic effects of hypotension and hypox-
                     • Devereaux PJ, Yang H, Yusuf S, et al. Effects of extended-release   emia seen with intravenous agents.
                    metoprolol succinate in patients undergoing non-cardiac surgery     • β-Blockers and amiodarone are the main agents used for periop-
                    (POISE  trial):  a  randomised  controlled  trial.  Lancet.  May  31,   erative prevention of atrial fibrillation in cardiac surgery patients.
                    2008;371(9627):1839-1847.                              • Augmentation of mean arterial pressure, maintenance of cardiac
                     • Epstein SK, Faling J, Daly BDT, et al. Predicting complications   output, and monitoring and drainage of cerebrospinal fluid with a
                    after pulmonary resection. Chest. 1993;104:694.       lumbar drain are important adjunctive therapies to reduce rates of
                     • Fleisher LA, Beckman JA, Brown KA, et al. 2009 ACCF/AHA   paralysis following aortic surgery.
                    focused update on perioperative beta blockade incorporated into     • Cardiac  herniation  following  pneumonectomy and pericardial
                    the ACC/AHA 2007 guidelines on perioperative cardiovascular   patch breakdown is characterized by acute obstructive shock,
                    evaluation and care for noncardiac surgery.  J Am Coll Cardiol.   jugular venous distention, and discoloration of the upper torso.
                    November 24, 2009;54(22):e13-e118.                    The mortality rate is 50%; therefore, immediate recognition and
                     • Ford GT, Whitelaw WA, Rosenal TW, et al. Diaphragm function   surgical treatment are imperative.
                    after upper abdominal surgery in humans.  Am  Rev  Respir  Dis.     • Bilateral recurrent laryngeal nerve injury leads to acute, emergent
                    1983;127:431.                                         respiratory failure requiring intubation, followed by tracheostomy.
                     • Frazee RC, Roberts JW, Okeson GC, et al. Open versus laparo-
                    scopic cholecystectomy: a comparison of postoperative pulmo-
                    nary function. Ann Surg. 1991;213:651.             OVERVIEW OF POSTOPERATIVE CRITICAL CARE
                     • McFalls EO, Ward HB, Moritz TE, et al. Coronary-artery revas-
                    cularization before elective major vascular surgery. N Engl J Med.   The principles of postoperative management for general care and post-
                    December 30, 2004;351(27):2795-2804.               operative emergencies are often discussed only in depth in large surgical
                     • Milbrandt EB, Deppen S, Harrison PL, et al. Costs associated with   texts or specialized surgical service texts. Any critical care provider who
                                                                       cares for general surgical, cardiothoracic, neurosurgical, and trauma
                    delirium in mechanically ventilated patients. Crit Care Med. April   patients should have a basic understanding of routine postoperative
                    2004;32(4):955-962.                                care, including understanding of surgical drains, chest tubes, and wound
                     • Van den Bergh G, Wouters P, Weekers F, et al. Intensive     care. As with all aspects of patient care, communication with nursing,
                    insulin therapy in the critically ill patient.  N Engl J Med.   ancillary personnel, and other health care providers is essential to appro-
                    2001;345:1359.                                     priate recognition and care for the emergencies. Communication with
                                                                       the anesthesia and surgical teams bringing the patient to the ICU should
                                                                       occur to ensure that the critical care provider understands what surgical
                                                                       procedure occurred, what events are expected, and what potential com-
                 REFERENCES                                            plications to watch for. The critical care unit should furthermore have
                                                                       appropriate equipment to assist in recognition and, when appropriate,
                 Complete references available online at www.mhprofessional.com/hall  treatment of these emergencies. Much of the critical care management of








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