Page 139 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 6 ■ Erythrocytes: Hemoglobin 123

+
HO CO → HCO Formation of Heme from Porphyrin

H m (F . . ) m x
T k - m . O ,

x m , k m m m m ( -

m . ) . H m -

+
HCO → H + HCO − m m

m .
F T m m x

m x m (C ) - m z m . T m -
−
. T . (F . . ) -C A

B k m . I m - m . A

m , k m III,

x m m . I z m ,

. IX

A x m x- m .

x T m ,

m m. I m m, x m - m m , -

x . T x- z m A (C A) . A

m m , m m -

m m m . x - m

T m m (ALA). T

x m m . T z m q m B . T m m -

x m x f . A x m m

% x m -ALA, z z m ALA -

. . T z m

x
BIOSYN HESIS OF HEMOGLOBIN ( m B ).

F m -ALA m -
S m m , m.

m m : A, A , F, m m ALA m m

m . N m m A m (PBG). T z

m . T A/A. I z m ALA . F m PBG

- m - m I III.

: . T III m , -

G m III , .

m T , m ,

m m m . T m

m . O - m m . F x

k m k m . (F )
+
T m j m m m - z m m . T m

. H m z m - m m , m

m . A x m % m m

m z x , .

m % z -

. T m m -

, m , m ( . ). V The Role of Iron in Hemoglobin Synthesis

m . I , m m

T
x

■ k .

■ I m m .

■ I k .

■ I k m .

■ m k M m m m

■ ; m m

■ m ( x m , m - m m x

m , m ) m . T , m ,