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124            PART 2  ■  Hematopoiesis and Cellular Maturation







                    TABLE        6.1         Values in the Measurement of Erythrocytes





                                                                     Normal Adult Values




                                                                     Men                                                                               Women




                                                                     Conventional Units                           SI                                   Conventional Units                       SI




                   Hematocrit

                   Packed cell volume                                41.5%–50.4%                                  0.415–0.504 L/L                      36%–45%                                  0.36–0.45 L/L


                   Erythrocyte count                                 4.5–5.9 × 10 /µL                             4.5–5.9 × 10 /L                      4.5–5.1 × 10 /µL                         4.5–5.1 × 10 /L
                                                                                                                                                                                                                   12
                                                                                                                                    12
                                                                                        6
                                                                                                                                                                         6
                   Hemoglobin

                   Concentration                                     14.0–18.0 g/dL                               145–180 g/L                          12.0–16.0 g/dL                           120–160 g/L

                   Normal value of MCV                               80–96                                        80–96 fL                             80–96                                    80–96 fL


                   Normal value of MCH                               27.5–33.2                                    27.5–33.2 pg                         27.5–33.2                                27.5–33.2 pg


                   Normal value of MCHC                              33.4%–35.6%                                  32–36 g/dL                           33.4%–35.6%                              32–36 g/dL

                   Representative Average Pediatric Values


                   At birth (cord blood)


                   Packed cell volume                                51%


                   Erythrocyte count                                 4.7 × 10 /L
                                                                                 12
                   Hemoglobin concentration                          16.5 g/dL


                   MCV                                               108 fL


                   MCH                                               34 pg


                   At 6–12 y of age

                   Packed cell volume                                40%


                   Erythrocyte count                                 4.6 × 10 /L
                                                                                 12

                   Hemoglobin concentration                          13.5 g/dL


                   MCV                                               86 fL

                   MCH                                               29 pg



                   SI, Systeme International d'Unites.

                   Source: Perkins SL. Normal blood and bone marrow values in humans. In: Greer JP, et al. (eds). Wintrobe’s Clinical Hematology, 11th ed, Philadelphia, PA:
                   Lippincott Williams & Wilkins, 2004:2607; Handin RI, Lux SE, Stossel TP. Blood, 2nd ed, Philadelphia, PA: Lippincott Williams & Wilkins, 2003:2216, Appendix 25

                   Red Blood Cell Values at Various Ages.

                   One femtoliter (fL) = 10  L = 1 cubic micrometer; one picogram (pg) = 10  g = 1 micromicrogram.
                                                                                                              12
                                                15




                                               .  %                                                                             F                    m

                  m                    m                            m                                                                             . F                  x                            m       m

               m                                . M                                                                                                          ,     m m

                   m         m                              ,                                     m                                                                       ,            m

                               mL    RBC                                            . I         -                                        . H             (        m                          C               )

                     ,                 m                                   m             ,                                                         m                                                m

                                  ,             m                                       x                                               m                                    ,           ,                 m   -

                                                                .                                                                     m      m                                                            k

                    I                       m,                                                                                                                     .  F                   x

               (+  )                  k              m                         m                                                m        m                                      ,      m  m

                                                                                        m             -                                                       ,              m

                           (DM    ). DM                m                          k                                               (F   .   .  ).

                                                            . O                     ,        m                                  I               m  ,                 (+  )                             ,

                                                                           x                                -                                                                             m  m                   -

                                                                           ,                     (       ).                          ,                               (   R). I
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