Page 359 - Clinical Hematology_ Theory _ Procedures ( PDFDrive )

CHAPTER 18 ■ Disorders of Granulocytes and Monocytes 343

GRANULOPOIE IC AL ERA IONS:

QUALI A IVE DISORDERS

Defective Locomotion and Chemotaxis

D m , m x

q . S

z k m k .

L k m m m -

m .

I ,

m x m m -

, C é k-H m . D k
FIGURE 18.7 C é k-H m . m .

(R m M C KD. Clinical Laboratory Medicine,

, P , PA: L W m & W k , , Lazy Leukocyte Syndrom e

m .)
Lazy leukocyte syndrome m

m z , -
Alder-Reilly Inclusions , m m (chemokinesis)

Alder Reilly inclusions - ( m x ) m
m. T m - m z .

m , , C , m , m
(F . . ). O , m - m k ,

m . T m z m z . A
m m . m z q m -

T m x - . M - ,
. A -R m mm WDR1, k , -

H ’ , H ’ , M x-L m - m z m z -
m m . A A m x m k m k

B (M x-L m m , m k m , -
m ) m x , m x

m (GAG ) ( ). M . T m
m m m WDR

.
Leukocyte Adhesion De ciency

Leukocyte adhesion de ciency (LAD) m -
NOTE: This is a good time to complete Review Questions . P

related to preceding content. LAD m -

, ,

k , m . P -

q - ,

( . × /L).

LAD

m m .

LAD m .

A . T

LAD :

LAD- LAD- .

LAD-1

LAD- . LAD-

β - (CD ). T -

, m , .

FIGURE 18.8 A -R m m m

. M . (R m LAD-2
M C KD. Clinical Laboratory Medicine, , P , LAD- m M

PA: L W m & W k , , m .) E B z . LAD-