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558    UNIT V  Middle Range Nursing Theories

            MAJOR CONCEPTS & DEFINITIONS—cont’d
            New View of Life                             Probabilistic Thinking
            New view of life refers to the formulation of a new   Probabilistic  thinking  refers  to  a  belief  in  a  condi-
            sense of order, resulting from the integration of con-  tional world in which the expectation of continual
            tinual uncertainty into one’s self-structure, in which   certainty  and  predictability  is  abandoned  (Mishel,
            uncertainty is accepted as the natural rhythm of life   1988).
            (Mishel, 1988).




            Use of Empirical Evidence                    et  al.,  1993;  Kim,  Lee,  &  Lee,  2012;  Murray,  1993).
           The Uncertainty in Illness Theory grew out of Mishel’s   Similarly, the ambiguous nature of illness symptoms
           dissertation research with hospitalized patients, using   and the consequent difficulty in determining the sig-
           both qualitative and quantitative findings to generate   nificance of physical sensations have been identified
           the first conceptualization of uncertainty in the context   as sources of uncertainty (Cohen, 1993; Hilton, 1988;
           of illness. With the publication of Mishel’s Uncertainty   Nelson, 1996).
           in  Illness  Scale  (Mishel,  1981),  extensive  research    Social  support  has  been  shown  to  have  a  direct
           began into adults’ experiences with uncertainty related   impact  on  uncertainty  by  reducing  perceived  com-
           to chronic and life-threatening illnesses. Considerable   plexity and an indirect impact through its effect on the
           empirical evidence has accumulated to support Mishel’s   predictability of symptom pattern (Lin, 2012; Mishel
           theoretical model in adults. Several integrative reviews   & Braden, 1988; Somjaivong, Thanasilp, Preechawong,
           of uncertainty research have comprehensively summa-  et  al.,  2011;  Scott,  Martin,  Stone,  et  al.,  2011).  The
           rized  and  critiqued  the  state  of  the  science  (Cahill,    perception of stigma associated with some conditions,
           Lobiondo-Wood,  Bergstrom,  et  al.,  2012;  Hansen,   particularly HIV infection (Regan-Kubinski & Sharts-
           Rørtveit,  Leiknes,  et  al.,  2012;  Mishel,  1997a,  1999;   Hopko,  1995)  and  Down’s  syndrome  (Van  Riper
           Stewart & Mishel, 2000). The authors included studies   &  Selder,  1989),  served  to  create  uncertainty  when
           that directly support the elements of Mishel’s uncer-  families were unsure about how others would respond
           tainty model.                                 to the diagnosis. Family members have been shown to
             Most empirical studies have been focused on two   experience  high  levels  of  uncertainty  as  well,  which
           antecedents of uncertainty, stimuli frame and structure   may  further  reduce  the  amount  of  support  experi-
           providers,  and  the  relationship  between  uncertainty   enced by the patient (Baird & Eliasziw, 2011; Brown
           and psychological outcomes. Mishel tested other ele-  & Powell-Cope, 1991; Hilton, 1996; Wineman, O’Brien,
           ments  of  the  model,  such  as  the  mediating  roles  of    Nealon, et al., 1993). Uncertainty was heightened by
           appraisal and coping, early in her program of research   interactions with health care providers when patients
           (Mishel & Braden, 1987; Mishel, Padilla, Grant, et al.,   and  family  members  received  unclear  information,
           1991; Mishel & Sorenson, 1991), and these elements, as   received simplistic explanations that did not fit their
           well as cognitive capacity as an antecedent to uncer-  experience, or perceived that care providers were not
           tainty, generated less research attention.    expert  or  responsive  enough  to  help  them  manage
             Several  studies  have  shown  that  objective  or    the  intricacies  of  the  illness  (Becker,  Jason-Bjerklie,
           subjective indicators of the severity of life-threat or   Benner, et al., 1993; Checton & Greene, 2012; Sharkey,
           illness symptoms associate positively with uncertainty   1995; Step & Ray, 2011).
           (Baird  &  Eliasziw,  2011;  Grootenhuis  &  Last,  1997;   Numerous studies have reported the negative impact
           Somjaivong,  Thanasilp,  Preechawong,  et  al.,  2011).   of uncertainty on psychological outcomes, characterized
           Across a sustained illness trajectory, unpredictability   variously as anxiety, depression, hopelessness, psycho-
           in symptom onset, duration, and intensity has been   logical distress (Arroll, Dancey, Attree, et al., 2012; Failla,
           related  to  perceived  uncertainty  (Arroll,  Dancey,    Kuper, Nick, et al., 1996; Grootenhuis & Last, 1997; Kim
           Attree,  et  al.,  2012;  Becker,  Jason-Bjerklie,  Benner,    &  So,  2012;  Miles,  Funk,  &  Kasper,  1992;  Mishel  &
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