Page 54 - B.Tech Biotech Curriculum and Syllabus R2017 - REC
P. 54

Department of BIOTECHNOLOGY, REC


                   Genbank.
                   Protein Data Bank.
                   Uniprot.
                   Pfam
                   CATH

            Sequence Analysis Tools
                   Use of BLAST, FASTA (Nucleic Acids &Protiens).
                   Use of Clustal W.
                   Use of EMBOSS.

            Phylogenetic Analysis
                   Use of Phyllip.

            Molecular Modeling
                   Homology Modeling – Swissmodeller.

            UCSC Genome Browser
            Protein Pathway Analysis
            Programming Languages: R for biological data analysis

                                                                                       TOTAL : 30 PERIODS
            COURSE OUTCOMES:
            Upon completion of this course, students will be able:
                 To understand basic commands in UNIX OS.
                 To use different biological databases.
                 To carry out sequence and phylogenetic analysis.
                 To use genome browsers
                 To study protein interaction pathways



            BT17601              BIOPHARMACEUTICAL TECHNOLOGY                                     L T P C
                                                                                                   3  0  0  3

            OBJECTIVES:
                 The aim of the course is to give strong foundation and advanced information on biopharmaceutical
                   aspects in relation to drug development. This course provides core responsibilities for the
                   development and monitoring of the drug and the preparation of medicines according to the norms.
                 To gain knowledge in physicochemical properties, pharmacology and the formulation of commonly
                   used biopharmaceuticals.

            UNIT I        INTRODUCTION                                                                   9
            Pharmaceutical industry & development of drugs; types of therapeutic agents and their uses; and regulatory
            aspects .


            UNIT II       DRUG ACTION, METABOLISM AND PHARMACOKINETICS                                   9
            Route of drug administration, pharmacodynamics, pharmacokinetics – Absorption, Distribution, Metabolism
            and Excretion of drugs / metabolites, prodrugs, protein binding of drugs

            UNIT III PRINCIPLES OF DRUG MANUFACTURE                                                      9
            Solid  dosage  forms  –  introduction  to  types  of  tablets,  excipients,  granulation  techniques,  compression
            machinery, processing problems, Coated tablets - types – enteric coated tablets, film coated tablets and sugar
            coated tablets. Evaluation of coated tablets. Production of hard and soft gelatine capsules, liquid dosage form
            – suspension and emulsion. Semisolid dosage form – ointment, GMP

            Curriculum and Syllabus | B.Tech. Biotechnology | R2017                                    Page 54
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