Page 109 - First Aid for the USMLE Step 1 2020, Thirtieth edition [MedicalBooksVN.com]_Neat

BIOCHEmISTRY ``BIOCHEMISTRY—GENETICS BIOCHEmISTRY ``BIOCHEMISTRY—NUTRITION SECTION II 65

` `BIOCHEMISTRY—NUTRITION

Vitamins: fat soluble A, D, E, K. Absorption dependent on ileum Malabsorption syndromes with steatorrhea (eg,
and pancreas. Toxicity more common than cystic fibrosis and celiac disease) or mineral
for water-soluble vitamins because fat-soluble oil intake can cause fat-soluble vitamin
vitamins accumulate in fat. deficiencies.

Vitamins: water B 1 (thiamine: TPP) All wash out easily from body except B 12 and B 9
soluble B 2 (riboflavin: FAD, FMN) (folate). B 12 stored in liver for ~ 3–4 years. B 9
+
B 3 (niacin: NAD ) stored in liver for ~ 3–4 months.
B 5 (pantothenic acid: CoA) B-complex deficiencies often result in
B 6 (pyridoxine: PLP) dermatitis, glossitis, and diarrhea.
B 7 (biotin) Can be coenzymes (eg, ascorbic acid) or
+
B 9 (folate) precursors to coenzymes (eg, FAD, NAD ).
B 12 (cobalamin)
C (ascorbic acid)

FAS1_2019_01-Biochem.indd 65 11/7/19 3:16 PM