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184 SEcTioN ii Microbiology ` microbiology—systems Microbiology ` microbiology—systems

Sexually transmitted infections
Disease cliNical FeatUres orgaNism
AIDS Opportunistic infections, Kaposi sarcoma, HIV
lymphoma
Chancroid Painful genital ulcer with exudate, inguinal Haemophilus ducreyi (it’s so painful, you “do
A adenopathy A cry”)

Chlamydia Urethritis, cervicitis, epididymitis, Chlamydia trachomatis (D–K)
conjunctivitis, reactive arthritis, PID

Condylomata Genital warts, koilocytes HPV-6 and -11
acuminata
Genital herpes Painful penile, vulvar, or cervical vesicles and HSV-2, less commonly HSV-1
ulcers; can cause systemic symptoms such as
fever, headache, myalgia
Gonorrhea Urethritis, cervicitis, PID, prostatitis, Neisseria gonorrhoeae
epididymitis, arthritis, creamy purulent
discharge
Granuloma inguinale Painless, beefy red ulcer that bleeds readily on Klebsiella (Calymmatobacterium) granulomatis;
(Donovanosis) contact B cytoplasmic Donovan bodies (bipolar staining)
Uncommon in US seen on microscopy
B

Hepatitis B Jaundice HBV
Lymphogranuloma Infection of lymphatics; painless genital ulcers, C trachomatis (L1–L3)
venereum painful lymphadenopathy (ie, buboes)
Primary syphilis Painless chancre Treponema pallidum
Secondary syphilis Fever, lymphadenopathy, skin rashes,
condylomata lata

Tertiary syphilis Gummas, tabes dorsalis, general paresis, aortitis,
Argyll Robertson pupil
Trichomoniasis Vaginitis, strawberry cervix, motile in wet prep Trichomonas vaginalis

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