Page 631 - First Aid for the USMLE Step 1 2020, Thirtieth edition [MedicalBooksVN.com]_Neat

Renal ` RENAL—PhysioLogy Renal ` RENAL—PhysioLogy SeCTIOn III 587

Relative 1.90
concentrations along [TF/P] > 1 1.85 PAH Creatinine
proximal convoluted when solute is
reabsorbed less quickly
tubules than water or when solute 1.80 Inulin
is secreted 1.75 clearance = GFR
Urea
[TF/P] = 1 1.50
when solute 1.25 Cl −
and water are [Tubular K +
reabsorbed at the fluid] 1.00
same rate [Plasma] Osmolarity, Na +
0.75 HCO –
[TF/P] < 1 3
when solute 0.50
is reabsorbed more 0.25 Amino acids
quickly than water Glucose
0.0
0% 25% 50% 75% 100%
% Distance along PCT length

Tubular inulin  in concentration (but not amount) along the PCT as a result of water reabsorption.
+
+
Cl reabsorption occurs at a slower rate than Na in early PCT and then matches the rate of Na
−
reabsorption more distally. Thus, its relative concentration  before it plateaus.

FAS1_2019_14-Renal.indd 587 11/7/19 5:42 PM