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Strain and Strain Rate Imaging in Early Detection of Ventricular                        365
                          Systolic Dysfunction - is This The Best Investigation?



                 4.Coronary Artery Disease                          for evaluating right ventricular function or function of
                                                                    hearts with single-ventricle physiology.
                   Reduced LS  values in asymptomatic  patients even
                 without  wall motion  abnormalities is a strong pre-   In contrast to only EF analysis,new speckle tracking
                 dictor of stable ischemic  cardiomyopathy.LS after   echocardiogram utilizing strain ,strain rate parame-
                 reperfusion  therapy  is  an excellent predictor  of LV   ters have shown to reliably detect preclinical abnor-
                 remodelling  and adverse  events.LS  also  correlates   malities in both regional and global myocardial func-
                 well with regional extent of scar tissue as evaluated   tion at an early stage .[9]
                 by contrast MRI.[12]
                  A cuttoff value of -4.5 % for regional LS discriminates   Limitations of Strain,Strain rate imaging
                 between viable myocardium and scar tissue.[3]       Stain measurements are  not possible  in non sinus
                                                                    rhythms.
                  The postsystolic motion or index measured after aor-
                 tic valve closure is an important quantitative marker    STE requires good image acquisition  to delineate
                 for analysis of ischemic myocardium.               endocardial border
                  In transmural pathologies like myocardial infarction     The  STE  technique results  depend  critically  on the
                 where epi,mid and subendocardial functions are uni-  machine with which the analysis are made and they
                 formly affected and all LS,CS,RS show significant im-  are not  interchangeable  among different manufac-
                 pairement.[3]                                      tures.
                                                                     The tissue Doppler derived strain and strain rate has
                 5.Heart Failure And Dyssynchrony
                                                                    a limitation of angle dependency,noise interference ,
                   STE  plays  a vital role  in  understanding  mechanics   inter intra observer variability and strict dependence
                 of  heart  failure.Decreased  LS  but preserved  apical   on frame rate[7]
                 rotation mechanics  and variable  CS and RS are  the
                 hallmark Heart failure  with preserved  EF.When the    These  parameters  are technically  more challenging
                 HF syndrome progress from diastolic to systolic dys-  and require  further standardizations.Further  stud-
                 function the LV torsion and peak untwisting rate are   ies  are  required  to assess  the incremental value of
                 valso reduced.[12,4]                               strains acquired from 2D /3D datasets Prospective
                                                                    clinical trials for validation of this technique in large
                                                                    populations are still lacking.
                 6.Dilated Cardiomyopathy
                  DCM has shown impairement of all three strains(LS   Conclusion
                 ,CS and RS) and also decrease  in apical twist and
                 untwisting velocity.                                Strain imaging is an innovative technique for objec-
                                                                    tively quantifying myocardial mechanics. Quantifica-
                 7.Stress Cardiomyopathy                            tion of LS,RS,CS allows an accurate and reproducible
                                                                    assessment of segmental and global LV/RV function.
                  It is a form of reversible LV systolic dysfunction with   LS has been found to be the most useful and easy
                 transient apical ballooning.Here STE shows reduction   parameter obtained from apical views.
                 in various strains extendind beyond any single arteri-
                 al territory,also with reduced peak systolic strain and    STE is more comprehensive, feasible and reproduc-
                 strain rate in apical and basal regions differentiating   ible.
                 Stress Cardiomyopathy from ACS.                     Echocardiography is currently the most widely used
                                                                    method in  the  assessment  of  ventricular function.
                 Advantages of Strain,Strain rate imaging           Besides the traditional methods, , newer techniques

                   Deformation imaging  techniques (SR and S) have   should be introduced in clinical routine .Strain ,Strain
                 some important advantages over the standard ECHO   rate imaging is thus one amoung the best investiga-
                 techniques.  The main  benefit of regional  S and  SR   tion in early detection of LV dysfunction There is no
                 lies  in the rapid  and objective  detection of  regions   single ideal technique or parameter for this purpose,
                 with delayed or decreased deformation, while for tra-  so the  combination  of several  of the  other parame-
                 ditional echocardiographic  methods, one  has to de-  ters is also necessary in order to have more compre-
                 pend on subjective assessment for this information.   hensive information about different aspects of heart
                                                                    function in different clinical settings
                  Another advantage of this technique is its indepen-
                 dence of ventricular geometry,therefore, it is suitable



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