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Chapter 9  CARE OF THE PATIENT WITH CRITICAL HEMATOLOGIC NEEDS        413



                                5   TABLE 9–5  Medications That Can Be Used in Hematologic Needs (Continued)

                               Medication     Action             Uses          Precautions
                               Aminocaproic  Hemostatic agent    Disseminated   1.  Avoid rapid infusion
                               acid (Amicar)  helps control      intravascular    by regulating on IV
                                              excessive bleeding   coagulopathy   pump
                                              Inhibits           (DIC)         2.  Rapid infusion can
                                              plasminogen                         cause dysrhythmias,
                                              activator substance                 bradycardia, and
                                              and plasmin                         hypotension
                                                                               3.  Change the
                                                                                  administration site
                                                                                  immediately if
                                                                                  extravasation or
                                                                                  thrombophlebitis
                                                                                  occurs
                                                                               4.  Can cause renal
                                                                                  failure; watch the
                                                                                  BUN, creatinine, and
                                                                                  urinary output
                                                                               5.  Report symptoms
                                                                                  of myopathy like
                                                                                  myalgia, fever,                   Downloaded by [ Faculty of Nursing, Chiangmai University 5.62.158.117] at [07/18/16]. Copyright © McGraw-Hill Global Education Holdings, LLC. Not to be redistributed or modified in any way without permission.
                                                                                  myoglobinuria
                                                                               6.  Discontinue if signs
                                                                                  of DVT or PE develop
                               Anticoagulants See Chapter 3
                                              medications
                                              (see Table 3–9)
                               Dobutamine     Increases cardiac   Hypotension   1.  Use infusion pump to
                               (Dobutrex)     contractility by   related to       titrate continuous
                                              stimulating beta-1   septic shock   infusion according to
                                              myocardial                          the HR and BP
                                              receptors                        2.  Correct acidosis and
                                              Increases CO and                    hypovolemia prior to
                                              decreases PAOP                      initiating
                                              Increases                        3.  Check the VS
                                              conduction through                  frequently during
                                              AV node                             initial therapy then
                                              Decreases rhythm                    every 15 minutes
                                              disturbances                        after stabilizing
                                                                               4.  If marked increase
                                                                                  in HR, BP, or
                                                                                  dysrhythmias,
                                                                                  decrease the dose
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