Page 70 - Color_Atlas_of_Physiology_5th_Ed._-_A._Despopoulos_2003

A. Motor end-plate
Myelin sheath
Motor axon
1 Motor end-plate

Schwann
cell
Motor End-plate
Mitochondrion Nerve
Vesicle ending Finger

2 Postsynaptic Basement
folds membrane
Plate 2.9
Muscle fiber

3 Acetylcholine
vesicle Presynaptic membrane
Synaptic cleft with basement membrane
Nerve
ending Postsynaptic membrane (sarcolemma)
4 K +
ACh
Active Cholinergic γ
zone N-receptors
α α

Muscle fiber
2+
(Ca ) Na +
(Partly after Akert and Peper)
B. End-plate currents
1 Quantum 100-200 Quanta
2.7pA 4nA 400nA

0 1 2 3 0 1 2 3 0 1 2 3
Time (ms) Time (ms) Time (ms)
1 Single-channel current 2 Miniature end-plate 3 Nerve-induced 57
current end-plate current
(After Neher and Sakmann (1) and after Peper et al. (2))
Despopoulos, Color Atlas of Physiology © 2003 Thieme
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